163. Immunologische Folgen des Milzverlustes nach Splenektomie bei traumatischer Milzruptur

Translated title of the contribution: Immunologic changes following splenectomy for traumatic splenic rupture

H. J. Klotter, H. Schulte-Wissermann, K. Rückert, Rainer W G Gruessner

Research output: Contribution to journalArticle

Abstract

After splenectomy for traumatic spleen rupture, 97 patients were followed up 2-18 years later. None had suffered from the OPSI syndrome. In 53% of the splenectomized patients, Howell-Jolly bodies and statistically significant monocytosis were detected. Sintigraphically proven peritoneal splenosis was present in 75% of the patients; however, no specific filtration was demonstrated by dynamic scintigraphy. Of the patients without splenosis who were followed up, 15 had a significant reduction of the killing activity of neutrophile granulocytes, as well as decreased numbers of T-helper cells. The T4/T8 ratio was 1:0.

Original languageGerman
Pages (from-to)730
Number of pages1
JournalLangenbecks Archiv für Chirurgie
Volume369
Issue number1
DOIs
Publication statusPublished - Dec 1986
Externally publishedYes

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Keywords

  • Immunological changes
  • Traumatic splenic rupture

ASJC Scopus subject areas

  • Surgery

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