Immunomodulation in humans caused by beta-carotene and vitamin A

Rao H. Prabhala; Harinder S. Garewal; Frank L. Meyskens; Ronald R. Watson

doi:10.1016/S0271-5317(05)80139-3

Immunomodulation in humans caused by beta-carotene and vitamin A

Rao H. Prabhala, Harinder S. Garewal, Frank L. Meyskens, Ronald R. Watson

Health Promotion Sciences

Research output: Contribution to journal › Review article

23 Scopus citations

Abstract

Carotenoids and retinoids can stimulate some human immune responses. These include cytoine release with anti-tumor cell activity, increased natural killer cells and activated lymphocytes after both in vitro and in vivo treatment with beta carotene. Such stimulations seem only partly due to retinoids formed from carotenoid metabolism and may be due to effects caused by the structure of beta carotene. Changes in immune functions could explain in part the cancer resistance provided by high carotenoid or retinoid intakes in animals.

Original language	English (US)
Pages (from-to)	1473-1486
Number of pages	14
Journal	Nutrition Research
Volume	10
Issue number	12
DOIs	https://doi.org/10.1016/S0271-5317(05)80139-3
State	Published - Dec 1990

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Keywords

activated lymphocytes
beta carotene
cancer
natural killer cells

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

Cite this

Prabhala, R. H., Garewal, H. S., Meyskens, F. L., & Watson, R. R. (1990). Immunomodulation in humans caused by beta-carotene and vitamin A. Nutrition Research, 10(12), 1473-1486. https://doi.org/10.1016/S0271-5317(05)80139-3

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Access to Document

10.1016/S0271-5317(05)80139-3