Abstract
Carotenoids and retinoids can stimulate some human immune responses. These include cytoine release with anti-tumor cell activity, increased natural killer cells and activated lymphocytes after both in vitro and in vivo treatment with beta carotene. Such stimulations seem only partly due to retinoids formed from carotenoid metabolism and may be due to effects caused by the structure of beta carotene. Changes in immune functions could explain in part the cancer resistance provided by high carotenoid or retinoid intakes in animals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1473-1486 |
| Number of pages | 14 |
| Journal | Nutrition Research |
| Volume | 10 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1990 |
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Keywords
- activated lymphocytes
- beta carotene
- cancer
- natural killer cells
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Nutrition and Dietetics
Cite this
Immunomodulation in humans caused by beta-carotene and vitamin A. / Prabhala, Rao H.; Garewal, Harinder S.; Meyskens, Frank L.; Watson, Ronald R.
In: Nutrition Research, Vol. 10, No. 12, 1990, p. 1473-1486.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immunomodulation in humans caused by beta-carotene and vitamin A
AU - Prabhala, Rao H.
AU - Garewal, Harinder S.
AU - Meyskens, Frank L.
AU - Watson, Ronald R
PY - 1990
Y1 - 1990
N2 - Carotenoids and retinoids can stimulate some human immune responses. These include cytoine release with anti-tumor cell activity, increased natural killer cells and activated lymphocytes after both in vitro and in vivo treatment with beta carotene. Such stimulations seem only partly due to retinoids formed from carotenoid metabolism and may be due to effects caused by the structure of beta carotene. Changes in immune functions could explain in part the cancer resistance provided by high carotenoid or retinoid intakes in animals.
AB - Carotenoids and retinoids can stimulate some human immune responses. These include cytoine release with anti-tumor cell activity, increased natural killer cells and activated lymphocytes after both in vitro and in vivo treatment with beta carotene. Such stimulations seem only partly due to retinoids formed from carotenoid metabolism and may be due to effects caused by the structure of beta carotene. Changes in immune functions could explain in part the cancer resistance provided by high carotenoid or retinoid intakes in animals.
KW - activated lymphocytes
KW - beta carotene
KW - cancer
KW - natural killer cells
UR - http://www.scopus.com/inward/record.url?scp=0025598267&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025598267&partnerID=8YFLogxK
U2 - 10.1016/S0271-5317(05)80139-3
DO - 10.1016/S0271-5317(05)80139-3
M3 - Article
AN - SCOPUS:0025598267
VL - 10
SP - 1473
EP - 1486
JO - Nutrition Research
JF - Nutrition Research
SN - 0271-5317
IS - 12
ER -