Immunotherapy for pediatric solid tumors

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Although the cure rates for pediatric and adolescent cancer continue to increase, many solid tumor malignancies continue to have overall worse outcomes when compared to acute lymphoblastic leukemia and lymphomas. This is especially true for metastatic or recurrent solid tumors. Immunotherapy may impact how we treat these tumors. Although the number of immunotherapy clinical trials in pediatric patients has been small compared to adults, the results are promising even in patients with advanced disease and should be explored further. In this chapter we will review the different immunotherapeutic approaches that have and are being evaluated in the pediatric oncology setting.

Original languageEnglish (US)
Title of host publicationCancer Immunology: Cancer Immunotherapy for Organ-Specific Tumors
PublisherSpringer Berlin Heidelberg
Pages47-67
Number of pages21
ISBN (Print)9783662464106, 9783662464090
DOIs
StatePublished - Jan 1 2015

Keywords

  • Children
  • Immunotherapy
  • Solid tumor

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

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