Impact and cost-effectiveness of a comprehensive schistosomiasis japonica control program in the Poyang lake region of China

Qing Yu, Geng Ming Zhao, Xian Lin Hong, Eric A Lutz, Jia Gang Guo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Schistosomiasis japonica remains a significant public-health problem in China. This study evaluated cost-effectiveness of a comprehensive schistosomiasis control program (2003-2006). The comprehensive control program was implemented in Zhangjia and Jianwu (cases); while standard interventions continued in Koutou and Xiajia (controls). Incurred costs were documented and the schistosomiasis comprehensive impact index (SCI) and cost-effectiveness ratio (Comprehensive Control Program Cost/SCI) were applied. In 2003, prevalence of Schistosoma japonicum infection was 11.3% (Zhangjia), 6.7% (Jianwu), 6.5% (Koutou), and 8.0% (Xiajia). In 2006, the comprehensive control program in Zhangjia and Jianwu reduced infection to 1.6% and 0.6%, respectively; while Koutou and Xiajia had a schistosomiasis prevalence of 3.2% and 13.0%, respectively. The year-by-year SCIs in Zhangjia were 0.28, 105.25, and 47.58, with an overall increase in cost-effectiveness ratio of 374.9%-544.8%. The SCIs in Jianwu were 16.21, 52.95, and 149.58, with increase in cost-effectiveness of 226.7%-1,149.4%. Investment in Koutou and Xiajia remained static (US$10,000 unit cost). The comprehensive control program implemented in the two case villages reduced median prevalence of schistosomiasis 8.5-fold. Further, the cost effectiveness ratio demonstrated that the comprehensive control program was 170% (Zhangjia) and 922.7% (Jianwu) more cost-effective. This work clearly shows the improvements in both cost and disease prevention effectiveness that a comprehensive control program-approach has on schistosomiasis infection prevalence.

Original languageEnglish (US)
Pages (from-to)6409-6421
Number of pages13
JournalInternational Journal of Environmental Research and Public Health
Volume10
Issue number12
DOIs
StatePublished - Nov 28 2013

Fingerprint

Schistosomiasis japonica
Schistosomiasis
Lakes
Cost-Benefit Analysis
China
Costs and Cost Analysis
Infection
Schistosoma japonicum
Cost of Illness
Cost Control
Public Health

Keywords

  • Comprehensive control program
  • Cost-effectiveness
  • Poyang lake region
  • Schistosomiasis japonica

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Impact and cost-effectiveness of a comprehensive schistosomiasis japonica control program in the Poyang lake region of China. / Yu, Qing; Zhao, Geng Ming; Hong, Xian Lin; Lutz, Eric A; Guo, Jia Gang.

In: International Journal of Environmental Research and Public Health, Vol. 10, No. 12, 28.11.2013, p. 6409-6421.

Research output: Contribution to journalArticle

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abstract = "Schistosomiasis japonica remains a significant public-health problem in China. This study evaluated cost-effectiveness of a comprehensive schistosomiasis control program (2003-2006). The comprehensive control program was implemented in Zhangjia and Jianwu (cases); while standard interventions continued in Koutou and Xiajia (controls). Incurred costs were documented and the schistosomiasis comprehensive impact index (SCI) and cost-effectiveness ratio (Comprehensive Control Program Cost/SCI) were applied. In 2003, prevalence of Schistosoma japonicum infection was 11.3{\%} (Zhangjia), 6.7{\%} (Jianwu), 6.5{\%} (Koutou), and 8.0{\%} (Xiajia). In 2006, the comprehensive control program in Zhangjia and Jianwu reduced infection to 1.6{\%} and 0.6{\%}, respectively; while Koutou and Xiajia had a schistosomiasis prevalence of 3.2{\%} and 13.0{\%}, respectively. The year-by-year SCIs in Zhangjia were 0.28, 105.25, and 47.58, with an overall increase in cost-effectiveness ratio of 374.9{\%}-544.8{\%}. The SCIs in Jianwu were 16.21, 52.95, and 149.58, with increase in cost-effectiveness of 226.7{\%}-1,149.4{\%}. Investment in Koutou and Xiajia remained static (US$10,000 unit cost). The comprehensive control program implemented in the two case villages reduced median prevalence of schistosomiasis 8.5-fold. Further, the cost effectiveness ratio demonstrated that the comprehensive control program was 170{\%} (Zhangjia) and 922.7{\%} (Jianwu) more cost-effective. This work clearly shows the improvements in both cost and disease prevention effectiveness that a comprehensive control program-approach has on schistosomiasis infection prevalence.",
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