Impact of color calibration on breast biopsy whole slide image interpretation accuracy and efficiency

Elizabeth A. Krupinski, Louis D. Silverstein, Syed F. Hashmi, Anna R. Graham, Ronald S. Weinstein, Hans Roehrig

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Color LCD use is increasing in medical imaging especially in applications like telepathology. Standardized methods for calibrating, characterizing and profiling color displays have not been created. We used a validated calibration, characterization and profiling protocol for color medical imaging applications to determine if it impacts performance accuracy and interpretation time. 250 breast biopsy whole slide image (WSI) areas (half malignant, half benign) were displayed to 6 pathologists. In one condition the calibration protocol was used and in the other the same display was un-calibrated. Receiver Operating Characteristic area under the curve (Az) with the calibrated display was 0.8570 and with the un-calibrated one was 0.8488 (p = 0.4112). For interpretation time, the mean with the calibrated display was 4.895 sec and with the un-calibrated display was 6.304 sec (p = 0.0460). There is an advantage diagnostically using a properly calibrated and color-managed display and a significant advantage for potentially improving workflow via reduced viewing times.

Original languageEnglish (US)
Title of host publicationBreast Imaging - 12th International Workshop, IWDM 2014, Proceedings
PublisherSpringer-Verlag
Pages744-748
Number of pages5
ISBN (Print)9783319078861
DOIs
StatePublished - Jan 1 2014
Event12th International Workshop on Breast Imaging, IWDM 2014 - Gifu City, Japan
Duration: Jun 29 2014Jul 2 2014

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8539 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other12th International Workshop on Breast Imaging, IWDM 2014
CountryJapan
CityGifu City
Period6/29/147/2/14

Keywords

  • Color displays
  • color calibration
  • color management
  • diagnostic accuracy
  • pathology

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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  • Cite this

    Krupinski, E. A., Silverstein, L. D., Hashmi, S. F., Graham, A. R., Weinstein, R. S., & Roehrig, H. (2014). Impact of color calibration on breast biopsy whole slide image interpretation accuracy and efficiency. In Breast Imaging - 12th International Workshop, IWDM 2014, Proceedings (pp. 744-748). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 8539 LNCS). Springer-Verlag. https://doi.org/10.1007/978-3-319-07887-8_103