Implementation of a decentralized community-based treatment program to improve the management of Buruli ulcer in the Ouinhi district of Benin, West Africa

Arnaud Setondji Amoussouhoui, Ghislain Emmanuel Sopoh, Anita Carolle Wadagni, Roch Christian Johnson, Paulin Aoulou, Inès Elvire Agbo, Jean Gabin Houezo, Micah Boyer, Mark Nichter

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Mycobacterium ulcerans infection, commonly known as Buruli ulcer (BU), is a debilitating neglected tropical disease. Its management remains complex and has three main components: antibiotic treatment combining rifampicin and streptomycin for 56 days, wound dressings and skin grafts for large ulcerations, and physical therapy to prevent functional limitations after care. In Benin, BU patient care is being integrated into the government health system. In this paper, we report on an innovative pilot program designed to introduce BU decentralization in Ouinhi district, one of Benin’s most endemic districts previously served by centralized hospital-based care. Methodology/Principal findings: We conducted intervention-oriented research implemented in four steps: baseline study, training of health district clinical staff, outreach education, outcome and impact assessments. Study results demonstrated that early BU lesions (71% of all detected cases) could be treated in the community following outreach education, and that most of the afflicted were willing to accept decentralized treatment. Ninety-three percent were successfully treated with antibiotics alone. The impact evaluation found that community confidence in decentralized BU care was greatly enhanced by clinic staff who came to be seen as having expertise in the care of most chronic wounds. Conclusions/Significance: This study documents a successful BU outreach and decentralized care program reaching early BU cases not previously treated by a proactive centralized BU program. The pilot program further demonstrates the added value of integrated wound management for NTD control.

Original languageEnglish (US)
Article numbere0006291
JournalPLoS Neglected Tropical Diseases
Volume12
Issue number3
DOIs
StatePublished - Mar 12 2018

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Buruli Ulcer
Benin
Western Africa
Therapeutics
Wounds and Injuries
Community-Institutional Relations
Neglected Diseases
Anti-Bacterial Agents
Education
Health
Streptomycin
Politics
Rifampin
Bandages
Patient Care
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Implementation of a decentralized community-based treatment program to improve the management of Buruli ulcer in the Ouinhi district of Benin, West Africa. / Amoussouhoui, Arnaud Setondji; Sopoh, Ghislain Emmanuel; Wadagni, Anita Carolle; Johnson, Roch Christian; Aoulou, Paulin; Agbo, Inès Elvire; Houezo, Jean Gabin; Boyer, Micah; Nichter, Mark.

In: PLoS Neglected Tropical Diseases, Vol. 12, No. 3, e0006291, 12.03.2018.

Research output: Contribution to journalArticle

Amoussouhoui, Arnaud Setondji ; Sopoh, Ghislain Emmanuel ; Wadagni, Anita Carolle ; Johnson, Roch Christian ; Aoulou, Paulin ; Agbo, Inès Elvire ; Houezo, Jean Gabin ; Boyer, Micah ; Nichter, Mark. / Implementation of a decentralized community-based treatment program to improve the management of Buruli ulcer in the Ouinhi district of Benin, West Africa. In: PLoS Neglected Tropical Diseases. 2018 ; Vol. 12, No. 3.
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