Improved synthesis of d,l-fluorocitric acid

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

We propose a decagram synthesis of commercially unavailable fluorocitric acid. The synthesis begins with benzyl fluoroacetate, which is converted to dibenzyl 2-fluoro-3-oxosuccinate, followed by condensation with malonic acid or its monobenzyl ester and subsequent hydrogenolysis.

Original languageEnglish (US)
Pages (from-to)920-924
Number of pages5
JournalJournal of Fluorine Chemistry
Volume132
Issue number11
DOIs
StatePublished - Nov 1 2011

Keywords

  • Fluorocitric acid

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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