In vivo Doppler flow imaging of picoliter blood volumes using optical coherence tomography

Joseph A. Izatt, Manish D. Kulkarni, Jennifer K. Barton, Ashley J. Welch

Research output: Contribution to journalConference article

3 Scopus citations

Abstract

An optical Doppler flow sensing technique is presented which is capable of micron-scale spatial resolution tomographic flow mapping in vivo. Optical coherence tomography was adapted for quantitative measurements of flow in scattering media by implementing algorithms for coherent signal acquisition and processing. The interferometric data is spectrally analyzed. A sequence of pulses were stored where each pulse has transform limited width of 200 fs. The recorded spectral domain holograms were read out for over 24 hours, indicating that the photorefractive hologram recorded with 460 nm wavelength is insensitive to the readout wavelength of 920 nm.

Original languageEnglish (US)
Pages (from-to)212-213
Number of pages2
JournalConference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS
Volume11
StatePublished - Jan 1 1997
Externally publishedYes
EventProceedings of the 1997 Conference on Lasers and Electro-Optics, CLEO - Baltimore, MD, USA
Duration: May 18 1997May 23 1997

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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