In vivo intestinal magnesium transport in rats: Normal and growth retarded

F. K. Ghishan, R. Meneely

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Protein-calorie malnutrition in infants and children is often accompanied by magnesium deficiency. The cause of this deficiency is not known. To assess the effect of growth retardation on intestinal magnesium transport, we studied with an in vivo single pass perfusion technique net magnesium transport in small and large intestinal segments of control and growth retarded suckling and adolescent rats. In small and large intestine of control suckling rats, rates of net magnesium transport were significantly greater than corresponding transport rates in adolescent rats. Net magnesium transport was similar between corresponding segments of control and growth retarded in both suckling and adolescent rats. Furthermore, tissue concentration of magnesium in liver, gut, kidney and blood was similar in control and growth retarded suckling and adolescent rats. The present study indicates that intestinal magnesium transport is unaltered in growth retarded infant or adult rats.

Original languageEnglish (US)
Pages (from-to)399-406
Number of pages8
JournalNutrition Reports International
Volume27
Issue number2
StatePublished - Jan 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science
  • Biochemistry
  • Endocrinology

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