Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review

Ayman El-Menyar, Ahammed Mekkodathil, Hassan Al-Thani, Rafael Consunji, Rifat - Latifi

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Background Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade. Methods Literature searches were conducted on PubMed, MEDLINE, and Google scholar electronic databases. The search terms used in different combinations were epidemiology, incidence, case fatality, mortality, intracranial injury, brain injury, head injury, and the country names. Additional searches were conducted using reference lists of studies and review articles for selection of relevant articles. The search yielded 1082 articles; of which 701 duplicates and 346 articles were excluded. Thirty-five original studies met the inclusion criteria. Data were extracted using standardized Excel form and pilot tested. Median with interquartile range (IQR) was used to estimate the incidence rate and mortality of TBI. Results In the Middle East region, the median TBI incidence rate per capita was 45 (IQR, 38.5–367) per 100,000. The overall median emergency department–based TBI mortality, which included all age groups and all injury severities, was 10% (IQR, 7.75–15.75). We estimated the overall median mortality for head trauma studies based on emergency department admissions as 6% (IQR, 3–18) among all age groups and all injury severities. The overall TBI-related median mortality in the intensive care unit–based studies was 25% (IQR, 15.5–47). Conclusions The epidemiology of TBI in the Middle East remains understudied. The use of a globally recognized definition of TBI will contribute greatly to improve its reporting, analysis, and interpretation and to establish appropriate injury prevention programs.

Original languageEnglish (US)
Pages (from-to)6-21
Number of pages16
JournalWorld Neurosurgery
Volume107
DOIs
StatePublished - Nov 1 2017
Externally publishedYes

Fingerprint

Middle East
Demography
Incidence
Mortality
Wounds and Injuries
Craniocerebral Trauma
Epidemiology
Age Groups
Traumatic Brain Injury
Critical Care
PubMed
MEDLINE
Brain Injuries
Names
Hospital Emergency Service
Emergencies
Public Health
Databases

Keywords

  • Brain
  • Epidemiology
  • Head
  • Injury
  • Middle East
  • Trauma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East : A Systematic Review. / El-Menyar, Ayman; Mekkodathil, Ahammed; Al-Thani, Hassan; Consunji, Rafael; Latifi, Rifat -.

In: World Neurosurgery, Vol. 107, 01.11.2017, p. 6-21.

Research output: Contribution to journalReview article

El-Menyar, Ayman ; Mekkodathil, Ahammed ; Al-Thani, Hassan ; Consunji, Rafael ; Latifi, Rifat -. / Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East : A Systematic Review. In: World Neurosurgery. 2017 ; Vol. 107. pp. 6-21.
@article{eae45f53c2cb4c398a8c6fc95a6f4c89,
title = "Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review",
abstract = "Background Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade. Methods Literature searches were conducted on PubMed, MEDLINE, and Google scholar electronic databases. The search terms used in different combinations were epidemiology, incidence, case fatality, mortality, intracranial injury, brain injury, head injury, and the country names. Additional searches were conducted using reference lists of studies and review articles for selection of relevant articles. The search yielded 1082 articles; of which 701 duplicates and 346 articles were excluded. Thirty-five original studies met the inclusion criteria. Data were extracted using standardized Excel form and pilot tested. Median with interquartile range (IQR) was used to estimate the incidence rate and mortality of TBI. Results In the Middle East region, the median TBI incidence rate per capita was 45 (IQR, 38.5–367) per 100,000. The overall median emergency department–based TBI mortality, which included all age groups and all injury severities, was 10{\%} (IQR, 7.75–15.75). We estimated the overall median mortality for head trauma studies based on emergency department admissions as 6{\%} (IQR, 3–18) among all age groups and all injury severities. The overall TBI-related median mortality in the intensive care unit–based studies was 25{\%} (IQR, 15.5–47). Conclusions The epidemiology of TBI in the Middle East remains understudied. The use of a globally recognized definition of TBI will contribute greatly to improve its reporting, analysis, and interpretation and to establish appropriate injury prevention programs.",
keywords = "Brain, Epidemiology, Head, Injury, Middle East, Trauma",
author = "Ayman El-Menyar and Ahammed Mekkodathil and Hassan Al-Thani and Rafael Consunji and Latifi, {Rifat -}",
year = "2017",
month = "11",
day = "1",
doi = "10.1016/j.wneu.2017.07.070",
language = "English (US)",
volume = "107",
pages = "6--21",
journal = "World Neurosurgery",
issn = "1878-8750",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Incidence, Demographics, and Outcome of Traumatic Brain Injury in The Middle East

T2 - A Systematic Review

AU - El-Menyar, Ayman

AU - Mekkodathil, Ahammed

AU - Al-Thani, Hassan

AU - Consunji, Rafael

AU - Latifi, Rifat -

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Background Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade. Methods Literature searches were conducted on PubMed, MEDLINE, and Google scholar electronic databases. The search terms used in different combinations were epidemiology, incidence, case fatality, mortality, intracranial injury, brain injury, head injury, and the country names. Additional searches were conducted using reference lists of studies and review articles for selection of relevant articles. The search yielded 1082 articles; of which 701 duplicates and 346 articles were excluded. Thirty-five original studies met the inclusion criteria. Data were extracted using standardized Excel form and pilot tested. Median with interquartile range (IQR) was used to estimate the incidence rate and mortality of TBI. Results In the Middle East region, the median TBI incidence rate per capita was 45 (IQR, 38.5–367) per 100,000. The overall median emergency department–based TBI mortality, which included all age groups and all injury severities, was 10% (IQR, 7.75–15.75). We estimated the overall median mortality for head trauma studies based on emergency department admissions as 6% (IQR, 3–18) among all age groups and all injury severities. The overall TBI-related median mortality in the intensive care unit–based studies was 25% (IQR, 15.5–47). Conclusions The epidemiology of TBI in the Middle East remains understudied. The use of a globally recognized definition of TBI will contribute greatly to improve its reporting, analysis, and interpretation and to establish appropriate injury prevention programs.

AB - Background Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade. Methods Literature searches were conducted on PubMed, MEDLINE, and Google scholar electronic databases. The search terms used in different combinations were epidemiology, incidence, case fatality, mortality, intracranial injury, brain injury, head injury, and the country names. Additional searches were conducted using reference lists of studies and review articles for selection of relevant articles. The search yielded 1082 articles; of which 701 duplicates and 346 articles were excluded. Thirty-five original studies met the inclusion criteria. Data were extracted using standardized Excel form and pilot tested. Median with interquartile range (IQR) was used to estimate the incidence rate and mortality of TBI. Results In the Middle East region, the median TBI incidence rate per capita was 45 (IQR, 38.5–367) per 100,000. The overall median emergency department–based TBI mortality, which included all age groups and all injury severities, was 10% (IQR, 7.75–15.75). We estimated the overall median mortality for head trauma studies based on emergency department admissions as 6% (IQR, 3–18) among all age groups and all injury severities. The overall TBI-related median mortality in the intensive care unit–based studies was 25% (IQR, 15.5–47). Conclusions The epidemiology of TBI in the Middle East remains understudied. The use of a globally recognized definition of TBI will contribute greatly to improve its reporting, analysis, and interpretation and to establish appropriate injury prevention programs.

KW - Brain

KW - Epidemiology

KW - Head

KW - Injury

KW - Middle East

KW - Trauma

UR - http://www.scopus.com/inward/record.url?scp=85031795231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85031795231&partnerID=8YFLogxK

U2 - 10.1016/j.wneu.2017.07.070

DO - 10.1016/j.wneu.2017.07.070

M3 - Review article

C2 - 28736357

AN - SCOPUS:85031795231

VL - 107

SP - 6

EP - 21

JO - World Neurosurgery

JF - World Neurosurgery

SN - 1878-8750

ER -