Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial

Cynthia Thomson, Cheryl L. Rock, Bette J. Caan, Shirley W. Flatt, Wael A. Al-Delaimy, Vicky A. Newman, Richard A. Hajek, Janice A. Chilton, John P. Pierce

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Consumption of cruciferous vegetables has been associated with reduced breast cancer risk mechanistically and in population-based studies, although evidence has been inconsistent. This inconsistency may be related to limitations in quantifying and qualifying cruciferous vegetable exposure using standard instruments for dietary assessment (for example, food-frequency questionnaires, FFQs) or due to low levels of intake demonstrated among U.S. population samples. Cruciferous vegetable intake data are presented from a longitudinal study of a high-vegetable dietary intervention to reduce breast cancer recurrence among breast cancer survivors (n = 1,156; 536 intervention and 620 comparison group subjects). Intake was assessed using repeat administration of an FFQ and cross-sectional administration of a cruciferous vegetable-specific FFQ (CVFFQ). Mean intake in the intervention group assessed using the standard FFQ was 37.7 g/day at baseline and increased to 57.1 g/day at 12 mo (P = 0.0001) and was sustained through 48 mo. Broccoli and cabbage were the most commonly consumed cruciferous vegetables, regardless of the instrument used to assess intake. Differences in intake by group assignment were shown for raw cruciferous vegetables (30.2 g/day vs. 24.6 g/day, assessed using the CVFFQ), suggesting increased exposure to biologically active, cancer-preventive food constituents. These data suggest that this study population will be the first U.S. population sample to provide ample quantity and variety in cruciferous intake to examine whether these vegetables are protective against breast cancer recurrence.

Original languageEnglish (US)
Pages (from-to)11-19
Number of pages9
JournalNutrition and Cancer
Volume57
Issue number1
StatePublished - 2007

Fingerprint

vegetable consumption
Vegetables
breast neoplasms
vegetables
food frequency questionnaires
Breast Neoplasms
Food
Brassica
Population
raw vegetables
broccoli
longitudinal studies
cabbage
Recurrence
sampling
neoplasms
Longitudinal Studies
Survivors
Surveys and Questionnaires

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Oncology
  • Food Science

Cite this

Thomson, C., Rock, C. L., Caan, B. J., Flatt, S. W., Al-Delaimy, W. A., Newman, V. A., ... Pierce, J. P. (2007). Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial. Nutrition and Cancer, 57(1), 11-19.

Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial. / Thomson, Cynthia; Rock, Cheryl L.; Caan, Bette J.; Flatt, Shirley W.; Al-Delaimy, Wael A.; Newman, Vicky A.; Hajek, Richard A.; Chilton, Janice A.; Pierce, John P.

In: Nutrition and Cancer, Vol. 57, No. 1, 2007, p. 11-19.

Research output: Contribution to journalArticle

Thomson, C, Rock, CL, Caan, BJ, Flatt, SW, Al-Delaimy, WA, Newman, VA, Hajek, RA, Chilton, JA & Pierce, JP 2007, 'Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial', Nutrition and Cancer, vol. 57, no. 1, pp. 11-19.
Thomson, Cynthia ; Rock, Cheryl L. ; Caan, Bette J. ; Flatt, Shirley W. ; Al-Delaimy, Wael A. ; Newman, Vicky A. ; Hajek, Richard A. ; Chilton, Janice A. ; Pierce, John P. / Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial. In: Nutrition and Cancer. 2007 ; Vol. 57, No. 1. pp. 11-19.
@article{9304c9feaee34ea7b2ed17c9d7d6cf67,
title = "Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial",
abstract = "Consumption of cruciferous vegetables has been associated with reduced breast cancer risk mechanistically and in population-based studies, although evidence has been inconsistent. This inconsistency may be related to limitations in quantifying and qualifying cruciferous vegetable exposure using standard instruments for dietary assessment (for example, food-frequency questionnaires, FFQs) or due to low levels of intake demonstrated among U.S. population samples. Cruciferous vegetable intake data are presented from a longitudinal study of a high-vegetable dietary intervention to reduce breast cancer recurrence among breast cancer survivors (n = 1,156; 536 intervention and 620 comparison group subjects). Intake was assessed using repeat administration of an FFQ and cross-sectional administration of a cruciferous vegetable-specific FFQ (CVFFQ). Mean intake in the intervention group assessed using the standard FFQ was 37.7 g/day at baseline and increased to 57.1 g/day at 12 mo (P = 0.0001) and was sustained through 48 mo. Broccoli and cabbage were the most commonly consumed cruciferous vegetables, regardless of the instrument used to assess intake. Differences in intake by group assignment were shown for raw cruciferous vegetables (30.2 g/day vs. 24.6 g/day, assessed using the CVFFQ), suggesting increased exposure to biologically active, cancer-preventive food constituents. These data suggest that this study population will be the first U.S. population sample to provide ample quantity and variety in cruciferous intake to examine whether these vegetables are protective against breast cancer recurrence.",
author = "Cynthia Thomson and Rock, {Cheryl L.} and Caan, {Bette J.} and Flatt, {Shirley W.} and Al-Delaimy, {Wael A.} and Newman, {Vicky A.} and Hajek, {Richard A.} and Chilton, {Janice A.} and Pierce, {John P.}",
year = "2007",
language = "English (US)",
volume = "57",
pages = "11--19",
journal = "Nutrition and Cancer",
issn = "0163-5581",
publisher = "Routledge",
number = "1",

}

TY - JOUR

T1 - Increase in cruciferous vegetable intake in women previously treated for breast cancer participating in a dietary intervention trial

AU - Thomson, Cynthia

AU - Rock, Cheryl L.

AU - Caan, Bette J.

AU - Flatt, Shirley W.

AU - Al-Delaimy, Wael A.

AU - Newman, Vicky A.

AU - Hajek, Richard A.

AU - Chilton, Janice A.

AU - Pierce, John P.

PY - 2007

Y1 - 2007

N2 - Consumption of cruciferous vegetables has been associated with reduced breast cancer risk mechanistically and in population-based studies, although evidence has been inconsistent. This inconsistency may be related to limitations in quantifying and qualifying cruciferous vegetable exposure using standard instruments for dietary assessment (for example, food-frequency questionnaires, FFQs) or due to low levels of intake demonstrated among U.S. population samples. Cruciferous vegetable intake data are presented from a longitudinal study of a high-vegetable dietary intervention to reduce breast cancer recurrence among breast cancer survivors (n = 1,156; 536 intervention and 620 comparison group subjects). Intake was assessed using repeat administration of an FFQ and cross-sectional administration of a cruciferous vegetable-specific FFQ (CVFFQ). Mean intake in the intervention group assessed using the standard FFQ was 37.7 g/day at baseline and increased to 57.1 g/day at 12 mo (P = 0.0001) and was sustained through 48 mo. Broccoli and cabbage were the most commonly consumed cruciferous vegetables, regardless of the instrument used to assess intake. Differences in intake by group assignment were shown for raw cruciferous vegetables (30.2 g/day vs. 24.6 g/day, assessed using the CVFFQ), suggesting increased exposure to biologically active, cancer-preventive food constituents. These data suggest that this study population will be the first U.S. population sample to provide ample quantity and variety in cruciferous intake to examine whether these vegetables are protective against breast cancer recurrence.

AB - Consumption of cruciferous vegetables has been associated with reduced breast cancer risk mechanistically and in population-based studies, although evidence has been inconsistent. This inconsistency may be related to limitations in quantifying and qualifying cruciferous vegetable exposure using standard instruments for dietary assessment (for example, food-frequency questionnaires, FFQs) or due to low levels of intake demonstrated among U.S. population samples. Cruciferous vegetable intake data are presented from a longitudinal study of a high-vegetable dietary intervention to reduce breast cancer recurrence among breast cancer survivors (n = 1,156; 536 intervention and 620 comparison group subjects). Intake was assessed using repeat administration of an FFQ and cross-sectional administration of a cruciferous vegetable-specific FFQ (CVFFQ). Mean intake in the intervention group assessed using the standard FFQ was 37.7 g/day at baseline and increased to 57.1 g/day at 12 mo (P = 0.0001) and was sustained through 48 mo. Broccoli and cabbage were the most commonly consumed cruciferous vegetables, regardless of the instrument used to assess intake. Differences in intake by group assignment were shown for raw cruciferous vegetables (30.2 g/day vs. 24.6 g/day, assessed using the CVFFQ), suggesting increased exposure to biologically active, cancer-preventive food constituents. These data suggest that this study population will be the first U.S. population sample to provide ample quantity and variety in cruciferous intake to examine whether these vegetables are protective against breast cancer recurrence.

UR - http://www.scopus.com/inward/record.url?scp=34249877709&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34249877709&partnerID=8YFLogxK

M3 - Article

C2 - 17516858

AN - SCOPUS:34249877709

VL - 57

SP - 11

EP - 19

JO - Nutrition and Cancer

JF - Nutrition and Cancer

SN - 0163-5581

IS - 1

ER -