Uvelichenie aktivnosti ornitindekarboksilazy i soderzhaniia poliaminov v pecheni krys v ranniǐ period gepatokantserogeneza.

Translated title of the contribution: Increase in ornithine decarboxylase activity and polyamine levels of the rat liver during an early period of hepatocarcinogenesis

N. K. Berdinskikh, S. P. Zaletok, Natalia Ignatenko, N. V. Draga

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The ornithine decarboxylase activity and the polyamine content in the fraction of plasma membranes and cytosol of the rat liver are studied in the early period (1-4 weeks) of nitrosodiethyl amine-induced hepatocarcinogenesis. The enzyme activity and polyamine levels in the cytosol of the rat liver cells are found to increase sharply during the first month of the disease, the maximum being observed the first-second week. By the end of the fourth week these indices become lower but they remain significantly higher than the normal levels. The polyamine level increases considerably in the fraction of plasma membranes with the maximum observed the second week.

Original languageUndefined/Unknown
Pages (from-to)94-97
Number of pages4
JournalUkrainskii biokhimicheskii zhurnal
Volume60
Issue number1
StatePublished - Jan 1988
Externally publishedYes

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Ornithine Decarboxylase
Polyamines
Liver
Rats
Cell membranes
Cytosol
Cell Membrane
Enzyme activity
Amines
Enzymes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

Uvelichenie aktivnosti ornitindekarboksilazy i soderzhaniia poliaminov v pecheni krys v ranniǐ period gepatokantserogeneza. / Berdinskikh, N. K.; Zaletok, S. P.; Ignatenko, Natalia; Draga, N. V.

In: Ukrainskii biokhimicheskii zhurnal, Vol. 60, No. 1, 01.1988, p. 94-97.

Research output: Contribution to journalArticle

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