Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.
|Original language||English (US)|
|Number of pages||5|
|Journal||Molecular and Cellular Biology|
|Publication status||Published - 1990|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology