Induction of the proto-oncogene c-jun by angiotensin II

A. J. Naftilan, G. K. Gilliland, C. S. Eldridge, Andrew Kraft

Research output: Contribution to journalArticle

133 Citations (Scopus)

Abstract

Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.

Original languageEnglish (US)
Pages (from-to)5536-5540
Number of pages5
JournalMolecular and Cellular Biology
Volume10
Issue number10
StatePublished - 1990
Externally publishedYes

Fingerprint

jun Genes
Angiotensin II
Smooth Muscle Myocytes
Transcription Factor AP-1
Vascular Smooth Muscle
Hypertrophy
Cell Culture Techniques
Growth

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Naftilan, A. J., Gilliland, G. K., Eldridge, C. S., & Kraft, A. (1990). Induction of the proto-oncogene c-jun by angiotensin II. Molecular and Cellular Biology, 10(10), 5536-5540.

Induction of the proto-oncogene c-jun by angiotensin II. / Naftilan, A. J.; Gilliland, G. K.; Eldridge, C. S.; Kraft, Andrew.

In: Molecular and Cellular Biology, Vol. 10, No. 10, 1990, p. 5536-5540.

Research output: Contribution to journalArticle

Naftilan, AJ, Gilliland, GK, Eldridge, CS & Kraft, A 1990, 'Induction of the proto-oncogene c-jun by angiotensin II', Molecular and Cellular Biology, vol. 10, no. 10, pp. 5536-5540.
Naftilan AJ, Gilliland GK, Eldridge CS, Kraft A. Induction of the proto-oncogene c-jun by angiotensin II. Molecular and Cellular Biology. 1990;10(10):5536-5540.
Naftilan, A. J. ; Gilliland, G. K. ; Eldridge, C. S. ; Kraft, Andrew. / Induction of the proto-oncogene c-jun by angiotensin II. In: Molecular and Cellular Biology. 1990 ; Vol. 10, No. 10. pp. 5536-5540.
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