Influence of injection site and route on medication absorption

Brian L Erstad, M. L. Meeks

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Concerns related to drug absorption are not limited to the oral route of administration. Medications given by various parenteral routes must also be absorbed to gain access to the systemic circulation. This article reviews the absorption characteristics of commonly administered medications by type and site of injection. The article focuses on four routes of parenteral injections: intramuscular, intralipomatous, subcutaneous, and intradermal. Differences in absorption relative to route or site of injection have been often demonstrated in studies, when such information was actively sought. Particularly important differences have been found with members of the following classes of medications: opiates, benzodiazepines, vaccines, insulins, and antiarrhythmics.

Original languageEnglish (US)
Pages (from-to)853-856+858
JournalHospital Pharmacy
Volume28
Issue number9
StatePublished - 1993

Fingerprint

Opiate Alkaloids
Insulins
Benzodiazepines
Vaccines
Injections
Pharmaceutical Preparations
Intramuscular Injections
Oral Administration

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Influence of injection site and route on medication absorption. / Erstad, Brian L; Meeks, M. L.

In: Hospital Pharmacy, Vol. 28, No. 9, 1993, p. 853-856+858.

Research output: Contribution to journalArticle

Erstad, Brian L ; Meeks, M. L. / Influence of injection site and route on medication absorption. In: Hospital Pharmacy. 1993 ; Vol. 28, No. 9. pp. 853-856+858.
@article{2a0bfd8577564c14b0e9334b306279f4,
title = "Influence of injection site and route on medication absorption",
abstract = "Concerns related to drug absorption are not limited to the oral route of administration. Medications given by various parenteral routes must also be absorbed to gain access to the systemic circulation. This article reviews the absorption characteristics of commonly administered medications by type and site of injection. The article focuses on four routes of parenteral injections: intramuscular, intralipomatous, subcutaneous, and intradermal. Differences in absorption relative to route or site of injection have been often demonstrated in studies, when such information was actively sought. Particularly important differences have been found with members of the following classes of medications: opiates, benzodiazepines, vaccines, insulins, and antiarrhythmics.",
author = "Erstad, {Brian L} and Meeks, {M. L.}",
year = "1993",
language = "English (US)",
volume = "28",
pages = "853--856+858",
journal = "Hospital Pharmacy",
issn = "0018-5787",
publisher = "Facts and Comparisons",
number = "9",

}

TY - JOUR

T1 - Influence of injection site and route on medication absorption

AU - Erstad, Brian L

AU - Meeks, M. L.

PY - 1993

Y1 - 1993

N2 - Concerns related to drug absorption are not limited to the oral route of administration. Medications given by various parenteral routes must also be absorbed to gain access to the systemic circulation. This article reviews the absorption characteristics of commonly administered medications by type and site of injection. The article focuses on four routes of parenteral injections: intramuscular, intralipomatous, subcutaneous, and intradermal. Differences in absorption relative to route or site of injection have been often demonstrated in studies, when such information was actively sought. Particularly important differences have been found with members of the following classes of medications: opiates, benzodiazepines, vaccines, insulins, and antiarrhythmics.

AB - Concerns related to drug absorption are not limited to the oral route of administration. Medications given by various parenteral routes must also be absorbed to gain access to the systemic circulation. This article reviews the absorption characteristics of commonly administered medications by type and site of injection. The article focuses on four routes of parenteral injections: intramuscular, intralipomatous, subcutaneous, and intradermal. Differences in absorption relative to route or site of injection have been often demonstrated in studies, when such information was actively sought. Particularly important differences have been found with members of the following classes of medications: opiates, benzodiazepines, vaccines, insulins, and antiarrhythmics.

UR - http://www.scopus.com/inward/record.url?scp=0027248982&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027248982&partnerID=8YFLogxK

M3 - Article

VL - 28

SP - 853-856+858

JO - Hospital Pharmacy

JF - Hospital Pharmacy

SN - 0018-5787

IS - 9

ER -