Influence of Malnutrition on the Concentration of IgA, Lysozyme, Amylase, and Aminopeptidase in Children's Tears

Ronald R. Watson, Marco A. Reyes, David N. Mcmurray

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Sixty-four pre-school-age children from a poor urban population in Colombia were studied to determine the influence of moderate to severe malnutrition on several proteins in the serum and tears. Secretory IgA, lysozyme, and amylase were found in significantly reduced concentrations in the tears of malnourished children. No influence of nutritional status on total proteins, albumin, and aminopeptidase was observed in this secretion. In the serum, IgA concentrations were significantly higher in the most malnourished group, while total proteins and albumin were reduced. These data suggest that increased susceptibility to infections of mucosal surfaces in malnourished children may be due to reduced concentrations of protective substances such as IgA and lysozyme in secretions.

Original languageEnglish (US)
Pages (from-to)215-219
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume157
Issue number2
DOIs
StatePublished - Feb 1978
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Influence of Malnutrition on the Concentration of IgA, Lysozyme, Amylase, and Aminopeptidase in Children's Tears'. Together they form a unique fingerprint.

  • Cite this