Inhibition of aspartic proteinases by propart peptides of human procathepsin D and chicken pepsinogen

M. Fusek, M. Mareš, J. Vágner, Z. Voburka, M. Baudyš

Research output: Contribution to journalArticle

40 Scopus citations


Two propart peptides of aspartic proteinases. the propart peptide of chicken pepsin and human cathepsin D, respectively, were investigated from the point of view of their inhibitory activity for a set of aspartic proteinases. These peptides display a very broad inhibitory spectrum. The strongest inhibition was observed for pepsin A-like proteinases where propart peptides can be used as titrants of active enzymes.

Original languageEnglish (US)
Pages (from-to)160-162
Number of pages3
JournalFEBS Letters
Issue number1-2
StatePublished - Aug 5 1991
Externally publishedYes



  • Aspartic proteinase
  • Chicken pepsinogen: Inhibition
  • Human procathepsin D
  • Propart peptide
  • Zymogen activation

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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