Inhibition of DNA transcription elongation and unwinding by bis-PNA

L. Bastide, G. Villani, P. Nielsen, Paul E Boehmer, B. Lebleu

Research output: Contribution to journalArticle

Abstract

The possibility to arrest transcription elongation by bis-PNA has been investigated. No arrest of transcription has been obtained in intact cells at variance with the data observed with purified RNA-polymerases. In keeping with these data a purified DNA-helicase (UL9) cannot be fully inhibited by such complexes.

Original languageEnglish (US)
Pages (from-to)1669-1671
Number of pages3
JournalNucleosides and Nucleotides
Volume18
Issue number6-7
StatePublished - 1999
Externally publishedYes

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DNA Helicases
DNA-Directed RNA Polymerases
Transcription
Elongation
DNA

ASJC Scopus subject areas

  • Biochemistry
  • Genetics

Cite this

Bastide, L., Villani, G., Nielsen, P., Boehmer, P. E., & Lebleu, B. (1999). Inhibition of DNA transcription elongation and unwinding by bis-PNA. Nucleosides and Nucleotides, 18(6-7), 1669-1671.

Inhibition of DNA transcription elongation and unwinding by bis-PNA. / Bastide, L.; Villani, G.; Nielsen, P.; Boehmer, Paul E; Lebleu, B.

In: Nucleosides and Nucleotides, Vol. 18, No. 6-7, 1999, p. 1669-1671.

Research output: Contribution to journalArticle

Bastide, L, Villani, G, Nielsen, P, Boehmer, PE & Lebleu, B 1999, 'Inhibition of DNA transcription elongation and unwinding by bis-PNA', Nucleosides and Nucleotides, vol. 18, no. 6-7, pp. 1669-1671.
Bastide, L. ; Villani, G. ; Nielsen, P. ; Boehmer, Paul E ; Lebleu, B. / Inhibition of DNA transcription elongation and unwinding by bis-PNA. In: Nucleosides and Nucleotides. 1999 ; Vol. 18, No. 6-7. pp. 1669-1671.
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