Abstract
Mouse antiserums prepared against la antigens, which are products of I (immune reponse) region genes of the H-2 complex, can inhibit both primary (immunoglobulin M) and secondary (immunoglobulin G) immune responses in vitro by mouse spleen cultures to heterologous erythrocytes. Antiserums directed specifically at products of either the H-2K or H-2D loci have no effect on this response.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 268-270 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 188 |
| Issue number | 4185 |
| DOIs | |
| State | Published - Jan 1 1975 |
| Externally published | Yes |
ASJC Scopus subject areas
- General
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Cite this
Frelinger, J. A., Niederhuber, J. E., & Shreffler, D. C. (1975). Inhibition of immune responses in vitro by specific antiserums to Ia antigens. Science, 188(4185), 268-270. https://doi.org/10.1126/science.1118728