TY - JOUR
T1 - Inhibition of immune responses in vitro by specific antiserums to Ia antigens
AU - Frelinger, Jeffrey A.
AU - Niederhuber, John E.
AU - Shreffler, Donald C.
PY - 1975/1/1
Y1 - 1975/1/1
N2 - Mouse antiserums prepared against la antigens, which are products of I (immune reponse) region genes of the H-2 complex, can inhibit both primary (immunoglobulin M) and secondary (immunoglobulin G) immune responses in vitro by mouse spleen cultures to heterologous erythrocytes. Antiserums directed specifically at products of either the H-2K or H-2D loci have no effect on this response.
AB - Mouse antiserums prepared against la antigens, which are products of I (immune reponse) region genes of the H-2 complex, can inhibit both primary (immunoglobulin M) and secondary (immunoglobulin G) immune responses in vitro by mouse spleen cultures to heterologous erythrocytes. Antiserums directed specifically at products of either the H-2K or H-2D loci have no effect on this response.
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U2 - 10.1126/science.1118728
DO - 10.1126/science.1118728
M3 - Article
C2 - 1118728
AN - SCOPUS:0016789876
VL - 188
SP - 268
EP - 270
JO - Science
JF - Science
SN - 0036-8075
IS - 4185
ER -