Integrated microfluidic systems for molecular diagnostics: A universal electrode platform for rapid diagnosis of urinary tract infections

Mandy L Y Sin, Vincent Gau, Joseph Liao, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Transforming microfluidics-based biosensing systems from laboratory research into clinical reality remains an elusive goal despite decades of intensive research. A fundamental obstacle in the development of fully automated microfluidic diagnostic systems is the lack of an effective strategy for combining multiple pumping, sample preparation, and detection modules into an integrated platform. In this article, we report a universal electrode approach, which incorporates dc electrolytic pumping, ac electrokinetic sample preparation, and electrochemical sensing based on a self-assembled monolayer (SAM) on a single microfluidic platform, to automate complicated molecular analysis procedures in nontraditional healthcare settings.

Original languageEnglish (US)
Title of host publicationIEEE Nanotechnology Magazine
Pages31-37
Number of pages7
Volume7
Edition1
DOIs
StatePublished - 2013

Fingerprint

Microfluidics
Electrodes
Self assembled monolayers
Research laboratories

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering

Cite this

Integrated microfluidic systems for molecular diagnostics : A universal electrode platform for rapid diagnosis of urinary tract infections. / Sin, Mandy L Y; Gau, Vincent; Liao, Joseph; Wong, Pak Kin.

IEEE Nanotechnology Magazine. Vol. 7 1. ed. 2013. p. 31-37 6450166.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sin, Mandy L Y ; Gau, Vincent ; Liao, Joseph ; Wong, Pak Kin. / Integrated microfluidic systems for molecular diagnostics : A universal electrode platform for rapid diagnosis of urinary tract infections. IEEE Nanotechnology Magazine. Vol. 7 1. ed. 2013. pp. 31-37
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