Integrating nanooptical biosensors into nucleic acid testing devices

Qi Huo Wei, Jian Gu, Chia Fu Chou, Frederic Zenhausern

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Nano optical biosensors employ the interaction between biomolecules and light confined in nanometer scale structures to report the bio-recognition events. This small scale sensing area/volume can ensure that small amount of biorecognition events could be detected. The exceptional sensitivity and high spatial density of nano optical biosensors make them unique in practical applications in nucleic acid detection. Lab-on-a-Chip systems provide the capabilities of separation, cell lysing, polymerase chain reaction (PCR), allowing finishing bio agent detection processes on a chip. In this paper, we present our recent efforts on integrating some novel nanooptical biosensors into Lab-on-a-Chip systems and some preliminary test results.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsG.E. Jabbour, J.T. Rantala
Pages45-53
Number of pages9
Volume5363
DOIs
StatePublished - 2004
EventEmerging Optoelectronic Applications - San Jose, CA, United States
Duration: Jan 26 2004Jan 27 2004

Other

OtherEmerging Optoelectronic Applications
CountryUnited States
CitySan Jose, CA
Period1/26/041/27/04

Fingerprint

Nucleic acids
nucleic acids
bioinstrumentation
Biosensors
systems-on-a-chip
Lab-on-a-chip
Testing
polymerase chain reaction
Polymerase chain reaction
Biomolecules
chips
sensitivity
cells
interactions

Keywords

  • Nano Optical Biosensors
  • Nucleic acid based bioprobes
  • Surface Plasmon Resonance

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Wei, Q. H., Gu, J., Chou, C. F., & Zenhausern, F. (2004). Integrating nanooptical biosensors into nucleic acid testing devices. In G. E. Jabbour, & J. T. Rantala (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5363, pp. 45-53) https://doi.org/10.1117/12.537799

Integrating nanooptical biosensors into nucleic acid testing devices. / Wei, Qi Huo; Gu, Jian; Chou, Chia Fu; Zenhausern, Frederic.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / G.E. Jabbour; J.T. Rantala. Vol. 5363 2004. p. 45-53.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wei, QH, Gu, J, Chou, CF & Zenhausern, F 2004, Integrating nanooptical biosensors into nucleic acid testing devices. in GE Jabbour & JT Rantala (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5363, pp. 45-53, Emerging Optoelectronic Applications, San Jose, CA, United States, 1/26/04. https://doi.org/10.1117/12.537799
Wei QH, Gu J, Chou CF, Zenhausern F. Integrating nanooptical biosensors into nucleic acid testing devices. In Jabbour GE, Rantala JT, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5363. 2004. p. 45-53 https://doi.org/10.1117/12.537799
Wei, Qi Huo ; Gu, Jian ; Chou, Chia Fu ; Zenhausern, Frederic. / Integrating nanooptical biosensors into nucleic acid testing devices. Proceedings of SPIE - The International Society for Optical Engineering. editor / G.E. Jabbour ; J.T. Rantala. Vol. 5363 2004. pp. 45-53
@inproceedings{65f229b24281452eb4114ea5ce5320e3,
title = "Integrating nanooptical biosensors into nucleic acid testing devices",
abstract = "Nano optical biosensors employ the interaction between biomolecules and light confined in nanometer scale structures to report the bio-recognition events. This small scale sensing area/volume can ensure that small amount of biorecognition events could be detected. The exceptional sensitivity and high spatial density of nano optical biosensors make them unique in practical applications in nucleic acid detection. Lab-on-a-Chip systems provide the capabilities of separation, cell lysing, polymerase chain reaction (PCR), allowing finishing bio agent detection processes on a chip. In this paper, we present our recent efforts on integrating some novel nanooptical biosensors into Lab-on-a-Chip systems and some preliminary test results.",
keywords = "Nano Optical Biosensors, Nucleic acid based bioprobes, Surface Plasmon Resonance",
author = "Wei, {Qi Huo} and Jian Gu and Chou, {Chia Fu} and Frederic Zenhausern",
year = "2004",
doi = "10.1117/12.537799",
language = "English (US)",
volume = "5363",
pages = "45--53",
editor = "G.E. Jabbour and J.T. Rantala",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - Integrating nanooptical biosensors into nucleic acid testing devices

AU - Wei, Qi Huo

AU - Gu, Jian

AU - Chou, Chia Fu

AU - Zenhausern, Frederic

PY - 2004

Y1 - 2004

N2 - Nano optical biosensors employ the interaction between biomolecules and light confined in nanometer scale structures to report the bio-recognition events. This small scale sensing area/volume can ensure that small amount of biorecognition events could be detected. The exceptional sensitivity and high spatial density of nano optical biosensors make them unique in practical applications in nucleic acid detection. Lab-on-a-Chip systems provide the capabilities of separation, cell lysing, polymerase chain reaction (PCR), allowing finishing bio agent detection processes on a chip. In this paper, we present our recent efforts on integrating some novel nanooptical biosensors into Lab-on-a-Chip systems and some preliminary test results.

AB - Nano optical biosensors employ the interaction between biomolecules and light confined in nanometer scale structures to report the bio-recognition events. This small scale sensing area/volume can ensure that small amount of biorecognition events could be detected. The exceptional sensitivity and high spatial density of nano optical biosensors make them unique in practical applications in nucleic acid detection. Lab-on-a-Chip systems provide the capabilities of separation, cell lysing, polymerase chain reaction (PCR), allowing finishing bio agent detection processes on a chip. In this paper, we present our recent efforts on integrating some novel nanooptical biosensors into Lab-on-a-Chip systems and some preliminary test results.

KW - Nano Optical Biosensors

KW - Nucleic acid based bioprobes

KW - Surface Plasmon Resonance

UR - http://www.scopus.com/inward/record.url?scp=3543124097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3543124097&partnerID=8YFLogxK

U2 - 10.1117/12.537799

DO - 10.1117/12.537799

M3 - Conference contribution

VL - 5363

SP - 45

EP - 53

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Jabbour, G.E.

A2 - Rantala, J.T.

ER -