Integration of Perceptual and Mnemonic Dysfunction

Sensory Auras Are Associated with Left Hemispheric Memory Impairment

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Memory function during the intracarotid amobarbital test was studied to test the hypothesis that left hemisphere memory impairment is associated with sensory auras. In a series of 37 patients undergoing preoperative evaluation for epilepsy surgery, the quantitative memory scores during amobarbital inactivation of right and left hemisphere were analyzed for correlation with habitual epileptic auras classified as either (a) experiential, forced emotion, or whole-body dysphoria or (b) sensory hallucinations and/or illusions or localized dysesthesias. The left hemispheric memory score impairment was significantly worse in association with auras classified as sensory hallucinations and/or illusions or localized dysesthesias compared with auras classified as experiential, forced emotion, or whole-body dysphoria (P < 0.05). This finding may assist in predicting left-sided hemispheric memory dysfunction in patients with seizures beginning as auras involving sensory material. The results suggest an integration of perceptual and mnemonic dysfunction in which sensory auras are associated with left hemispheric memory impairment.

Original languageEnglish (US)
Pages (from-to)423-432
Number of pages10
JournalEpilepsy and Behavior
Volume2
Issue number5
DOIs
StatePublished - Oct 2001

Fingerprint

Epilepsy
Amobarbital
Paresthesia
Hallucinations
Emotions
Seizures

Keywords

  • Amobarbital test
  • Aura
  • Epilepsy
  • Left hemisphere memory
  • Sensory-memory

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

@article{1855390c74924a01a207bc3948565abb,
title = "Integration of Perceptual and Mnemonic Dysfunction: Sensory Auras Are Associated with Left Hemispheric Memory Impairment",
abstract = "Memory function during the intracarotid amobarbital test was studied to test the hypothesis that left hemisphere memory impairment is associated with sensory auras. In a series of 37 patients undergoing preoperative evaluation for epilepsy surgery, the quantitative memory scores during amobarbital inactivation of right and left hemisphere were analyzed for correlation with habitual epileptic auras classified as either (a) experiential, forced emotion, or whole-body dysphoria or (b) sensory hallucinations and/or illusions or localized dysesthesias. The left hemispheric memory score impairment was significantly worse in association with auras classified as sensory hallucinations and/or illusions or localized dysesthesias compared with auras classified as experiential, forced emotion, or whole-body dysphoria (P < 0.05). This finding may assist in predicting left-sided hemispheric memory dysfunction in patients with seizures beginning as auras involving sensory material. The results suggest an integration of perceptual and mnemonic dysfunction in which sensory auras are associated with left hemispheric memory impairment.",
keywords = "Amobarbital test, Aura, Epilepsy, Left hemisphere memory, Sensory-memory",
author = "Weinand, {Martin E} and Labiner, {David M} and Ahern, {Geoffrey L}",
year = "2001",
month = "10",
doi = "10.1006/ebeh.2001.0236",
language = "English (US)",
volume = "2",
pages = "423--432",
journal = "Epilepsy and Behavior",
issn = "1525-5050",
publisher = "Academic Press Inc.",
number = "5",

}

TY - JOUR

T1 - Integration of Perceptual and Mnemonic Dysfunction

T2 - Sensory Auras Are Associated with Left Hemispheric Memory Impairment

AU - Weinand, Martin E

AU - Labiner, David M

AU - Ahern, Geoffrey L

PY - 2001/10

Y1 - 2001/10

N2 - Memory function during the intracarotid amobarbital test was studied to test the hypothesis that left hemisphere memory impairment is associated with sensory auras. In a series of 37 patients undergoing preoperative evaluation for epilepsy surgery, the quantitative memory scores during amobarbital inactivation of right and left hemisphere were analyzed for correlation with habitual epileptic auras classified as either (a) experiential, forced emotion, or whole-body dysphoria or (b) sensory hallucinations and/or illusions or localized dysesthesias. The left hemispheric memory score impairment was significantly worse in association with auras classified as sensory hallucinations and/or illusions or localized dysesthesias compared with auras classified as experiential, forced emotion, or whole-body dysphoria (P < 0.05). This finding may assist in predicting left-sided hemispheric memory dysfunction in patients with seizures beginning as auras involving sensory material. The results suggest an integration of perceptual and mnemonic dysfunction in which sensory auras are associated with left hemispheric memory impairment.

AB - Memory function during the intracarotid amobarbital test was studied to test the hypothesis that left hemisphere memory impairment is associated with sensory auras. In a series of 37 patients undergoing preoperative evaluation for epilepsy surgery, the quantitative memory scores during amobarbital inactivation of right and left hemisphere were analyzed for correlation with habitual epileptic auras classified as either (a) experiential, forced emotion, or whole-body dysphoria or (b) sensory hallucinations and/or illusions or localized dysesthesias. The left hemispheric memory score impairment was significantly worse in association with auras classified as sensory hallucinations and/or illusions or localized dysesthesias compared with auras classified as experiential, forced emotion, or whole-body dysphoria (P < 0.05). This finding may assist in predicting left-sided hemispheric memory dysfunction in patients with seizures beginning as auras involving sensory material. The results suggest an integration of perceptual and mnemonic dysfunction in which sensory auras are associated with left hemispheric memory impairment.

KW - Amobarbital test

KW - Aura

KW - Epilepsy

KW - Left hemisphere memory

KW - Sensory-memory

UR - http://www.scopus.com/inward/record.url?scp=0039783801&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0039783801&partnerID=8YFLogxK

U2 - 10.1006/ebeh.2001.0236

DO - 10.1006/ebeh.2001.0236

M3 - Article

VL - 2

SP - 423

EP - 432

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

SN - 1525-5050

IS - 5

ER -