Intraarterial cis-platinum for patients with inoperable skeletal tumors

G. M. Mavligit, R. Benjamin, Y. Z. Patt, N. Jaffe, V. Chuang, S. Wallace, J. Murray, A. Ayala, S. Johnston, Evan M Hersh, D. B. Calvo

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Abstract

Twenty-three patients with inoperable skeletal tumors were treated with intraarterial cis-platinum prior to attempted surgery. The antitumor effect of intraarterial cis-platinum was monitored clinically by radiologic imaging techniques and, whenever possible, evaluated histopathologically by examination of surgical or biopsy tumor specimens. Objective responses were noted in 12 patients (52%) and included 2 complete, 7 partial and 3 less-than-partial remissions lasting from 14 to 70 weeks. Limb-saving surgery or hemipelvectomy became subsequently feasible in four and one patients respectively. Preoperative intraarterial cis-platinum is a safe procedure which might be used effectively in combination with other, more conventional postoperative adjuvant chemotherapy against skeletal tumors.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalCancer
Volume48
Issue number1
DOIs
StatePublished - 1981
Externally publishedYes

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Cisplatin
Hemipelvectomy
Neoplasms
Adjuvant Chemotherapy
Extremities
Biopsy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Mavligit, G. M., Benjamin, R., Patt, Y. Z., Jaffe, N., Chuang, V., Wallace, S., ... Calvo, D. B. (1981). Intraarterial cis-platinum for patients with inoperable skeletal tumors. Cancer, 48(1), 1-4. https://doi.org/10.1002/1097-0142(19810701)48:1<1::AID-CNCR2820480102>3.0.CO;2-R

Intraarterial cis-platinum for patients with inoperable skeletal tumors. / Mavligit, G. M.; Benjamin, R.; Patt, Y. Z.; Jaffe, N.; Chuang, V.; Wallace, S.; Murray, J.; Ayala, A.; Johnston, S.; Hersh, Evan M; Calvo, D. B.

In: Cancer, Vol. 48, No. 1, 1981, p. 1-4.

Research output: Contribution to journalArticle

Mavligit, GM, Benjamin, R, Patt, YZ, Jaffe, N, Chuang, V, Wallace, S, Murray, J, Ayala, A, Johnston, S, Hersh, EM & Calvo, DB 1981, 'Intraarterial cis-platinum for patients with inoperable skeletal tumors', Cancer, vol. 48, no. 1, pp. 1-4. https://doi.org/10.1002/1097-0142(19810701)48:1<1::AID-CNCR2820480102>3.0.CO;2-R
Mavligit, G. M. ; Benjamin, R. ; Patt, Y. Z. ; Jaffe, N. ; Chuang, V. ; Wallace, S. ; Murray, J. ; Ayala, A. ; Johnston, S. ; Hersh, Evan M ; Calvo, D. B. / Intraarterial cis-platinum for patients with inoperable skeletal tumors. In: Cancer. 1981 ; Vol. 48, No. 1. pp. 1-4.
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AU - Wallace, S.

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