Intraarterial cis‐platinum for patients with inoperable skeletal tumors

G. M. Mavligit, R. Benjamin, Y. Z. Patt, N. Jaffe, V. Chuang, S. Wallace, J. Murray, A. Ayala, S. Johnston, E. M. Hersh, D. B. Calvo

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28 Scopus citations

Abstract

Twenty‐three patients with inoperable skeletal tumors were treated with intraarterial cis‐platinum prior to attempted surgery. The antitumor effect of intraarterial cis‐platinum was monitored clinically by radiologic imaging techniques and, whenever possible, evaluated histopathologically by examination of surgical or biopsy tumor specimens. Objective responses were noted in 12 patients (52%) and included 2 complete, 7 partial and 3 less‐than‐partial remissions lasting from 14 to 70 weeks. Limb‐saving surgery or hemipelvectomy became subsequently feasible in four and one patients respectively. Preoperative intraarterial cis‐platinum is a safe procedure which might be used effectively in combination with other, more conventional postoperative adjuvant chemotherapy against skeletal tumors.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalCancer
Volume48
Issue number1
DOIs
StatePublished - Jul 1 1981

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Mavligit, G. M., Benjamin, R., Patt, Y. Z., Jaffe, N., Chuang, V., Wallace, S., Murray, J., Ayala, A., Johnston, S., Hersh, E. M., & Calvo, D. B. (1981). Intraarterial cis‐platinum for patients with inoperable skeletal tumors. Cancer, 48(1), 1-4. https://doi.org/10.1002/1097-0142(19810701)48:1<1::AID-CNCR2820480102>3.0.CO;2-R