Introduction: organ involvement in the cardiometabolic syndrome.

Melvin R. Hayden, Craig S Stump, James R. Sowers

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The cardiometabolic syndrome is a construct associated with an increased risk of type 2 diabetes mellitus, cardiovascular disease (coronary artery disease, peripheral arterial disease, and stroke), chronic kidney disease, and the metabolic hepatopathy referred to as nonalcoholic fatty liver disease or nonalcoholic steatohepatitis. Thus, the term cardiometabolic syndrome includes all of these metabolic, islet, cardiovascular, renal, and hepatic disorders and clustering clinical syndromes.This overview of the cardiometabolic syndrome is designed to review the clinical complications and the end-organ cellular and extracellular matrix remodeling events that occur with the cardiometabolic syndrome.The MINER acronym will serve as an outline, representing: Myocardial and metabolic-hepatopathy, Intimal and islet, Neurovascular, Endothelial, and Renal oxidation-reduction (redox) stress and remodeling.

Original languageEnglish (US)
Pages (from-to)16-24
Number of pages9
JournalJournal of the CardioMetabolic Syndrome
Volume1
Issue number1
DOIs
StatePublished - Dec 2006
Externally publishedYes

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Oxidation-Reduction
Tunica Intima
Kidney
Peripheral Arterial Disease
Chronic Renal Insufficiency
Type 2 Diabetes Mellitus
Extracellular Matrix
Cluster Analysis
Coronary Artery Disease
Cardiovascular Diseases
Stroke
Liver
Non-alcoholic Fatty Liver Disease

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Introduction : organ involvement in the cardiometabolic syndrome. / Hayden, Melvin R.; Stump, Craig S; Sowers, James R.

In: Journal of the CardioMetabolic Syndrome, Vol. 1, No. 1, 12.2006, p. 16-24.

Research output: Contribution to journalArticle

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