Investigation of regularized neural networks for the computerized detection of mass lesions in digital mammograms

Matthew A. Kupinski, Maryellen L. Giger

Research output: Contribution to journalConference article


Computerized schemes are currently being developed at the University of Chicago to detect mass lesions in digital mammograms. Artificial neural networks play an important role in the detection of masses. Currently, features are extracted from potential lesion areas and sent through a neural network to decide whether the area is to be called a true lesion or a false detection. One of the most difficult aspects of dealing with artificial neural networks is to train them without over-training; in other words, to take both the bias and variance into account when training. Typically, an early stopping technique is employed; that is, the neural network is tested on an independent data set and training is stopped when the performance on this independent data set is maximized. In this paper the effectiveness of regularization is evaluated as a technique to minimize over-training. Regularization adds an extra term to the cost-function used in neural network training that penalizes over-complex results. The results of simulation studies will be presented along with results obtained using data of actual lesions and false positives from our computerized mass detection scheme.

Original languageEnglish (US)
Pages (from-to)1336-1339
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
StatePublished - Dec 1 1997
EventProceedings of the 1997 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Chicago, IL, USA
Duration: Oct 30 1997Nov 2 1997

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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