Isosorbide dinitrate oral spray in acute exacerbation of chronic congestive heart failure secondary to coronary artery disease

Alan Marmor, Adam Schneeweiss, Moshe Plich, David Blondheim, Tali Sharir, Joseph S Alpert

Research output: Contribution to journalArticle

4 Scopus citations


Lingual and buccal administration of isosorbide dinitrate (ISDN) oral spray is theoretically more rapid in onset of action than sublingual tablet administration because the drug is absorbed from the tablet only after its dissolution. We studied the effect and the pharmacodynamic time course of ISDN spray in patients with acute deterioration of chronic congestive heart failure (CHF).

Original languageEnglish (US)
Pages (from-to)1199-1200
Number of pages2
JournalThe American journal of cardiology
Issue number12
Publication statusPublished - May 1 1987
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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