Itraconazole treatment of experimental systemic candidiasis in Male rats

Michael L. Yozwiak, John N. Galgiani

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

After intravenous infection with Candida albicans, rats received daily doses of itraconazole for 3 days. All rats receiving 2·5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. With subsequent reduction of the itraconazole dose to 0·63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group.

Original languageEnglish (US)
Pages (from-to)125-126
Number of pages2
JournalMedical mycology
Volume25
Issue number2
DOIs
StatePublished - Jan 1 1987

ASJC Scopus subject areas

  • Infectious Diseases

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