Itraconazole treatment of experimental systemic candidiasis in Male rats

Michael L. Yozwiak, John N Galgiani

Research output: Contribution to journalArticle

Abstract

After intravenous infection with Candida albicans, rats received daily doses of itraconazole for 3 days. All rats receiving 2·5 mg kg-1 day-1 survived while all rats receiving sham-treatment died. With subsequent reduction of the itraconazole dose to 0·63 mg kg-1 day-1, no survival occurred and mortality rates equalled those of the control group.

Original languageEnglish (US)
Pages (from-to)125-126
Number of pages2
JournalMedical Mycology
Volume25
Issue number2
DOIs
StatePublished - 1987

Fingerprint

candidiasis
Itraconazole
itraconazole
rats
dosage
Candida albicans
placebos
Therapeutics
Survival Rate
survival rate
Placebos
Control Groups
Mortality
Infection
infection
Systemic candidiasis

ASJC Scopus subject areas

  • veterinary(all)
  • Infectious Diseases

Cite this

Itraconazole treatment of experimental systemic candidiasis in Male rats. / Yozwiak, Michael L.; Galgiani, John N.

In: Medical Mycology, Vol. 25, No. 2, 1987, p. 125-126.

Research output: Contribution to journalArticle

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