From data in dogs it is concluded that an appropriate I/E ratio (>0.25), peak airway pressures near 10 cm H2O, and end-expiratory pressures of <3 cm H2O are required for effective ventilation. General HFJV principles that may be extrapolated to humans suggest the necessity for maintaining a minimum lung volume and compliance for efficient gas exchange, possibly due to recruitment of distal airways, increased flow, and enhanced gas mixing. As expiratory resistance may be more significant in humans, higher I/E values may be clinically ineffective.
|Original language||English (US)|
|Number of pages||8|
|Journal||Anesthesia and analgesia|
|State||Published - Jan 1 1982|
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine