Junctional zone of the uterus

Correlation of MR imaging and histologic examination of hysterectomy specimens

Leslie M. Scoutt, Stuart D Flynn, Daniel J. Luthringer, Thomas R. McCauley, Shirley M. McCarthy

Research output: Contribution to journalArticle

112 Citations (Scopus)

Abstract

High-resolution magnetic resonance (MR) images of 12 hysterectomy specimens were correlated with results of light microscopy, image analysis, and immunohistochemical studies to investigate the histologic counterpart of the low-signal-intensity band, or junctional zone (JZ), that surrounds the bright central uterine stripe. All specimens were imaged with a 1.5-T superconducting magnet within 2 1/2 hours (on average) after hysterectomy. Comparison of histologic findings with measurements obtained at MR imaging indicates that the JZ represents the innermost layer of the myometrium. A threefold increase in percentage of nuclear area was found in the JZ in comparison with the outer myometrium, reflecting an increase in both size and number of nuclei. No difference in distribution of common components of the extracellular space (collagen, laminin, and fibronectin) was found between the two layers.

Original languageEnglish (US)
Pages (from-to)403-407
Number of pages5
JournalRadiology
Volume179
Issue number2
StatePublished - May 1991
Externally publishedYes

Fingerprint

Myometrium
Hysterectomy
Uterus
Magnetic Resonance Imaging
Extracellular Space
Laminin
Fibronectins
Microscopy
Magnetic Resonance Spectroscopy
Collagen
Light
Superconductivity

Keywords

  • Magnetic resonance (MR), tissue characterization
  • Uterus, anatomy, 854.92
  • Uterus, MR studies, 854.1214

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Scoutt, L. M., Flynn, S. D., Luthringer, D. J., McCauley, T. R., & McCarthy, S. M. (1991). Junctional zone of the uterus: Correlation of MR imaging and histologic examination of hysterectomy specimens. Radiology, 179(2), 403-407.

Junctional zone of the uterus : Correlation of MR imaging and histologic examination of hysterectomy specimens. / Scoutt, Leslie M.; Flynn, Stuart D; Luthringer, Daniel J.; McCauley, Thomas R.; McCarthy, Shirley M.

In: Radiology, Vol. 179, No. 2, 05.1991, p. 403-407.

Research output: Contribution to journalArticle

Scoutt, LM, Flynn, SD, Luthringer, DJ, McCauley, TR & McCarthy, SM 1991, 'Junctional zone of the uterus: Correlation of MR imaging and histologic examination of hysterectomy specimens', Radiology, vol. 179, no. 2, pp. 403-407.
Scoutt, Leslie M. ; Flynn, Stuart D ; Luthringer, Daniel J. ; McCauley, Thomas R. ; McCarthy, Shirley M. / Junctional zone of the uterus : Correlation of MR imaging and histologic examination of hysterectomy specimens. In: Radiology. 1991 ; Vol. 179, No. 2. pp. 403-407.
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