Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum

L. E. Perryman, Michael W Riggs, P. H. Mason, R. Fayer

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Monoclonal antibodies, immune bovine serum, and immune bovine colostral whey neutralized infectivity of Cryptosporidium parvum sporozoites for mice in a time-dependent manner. Immune colostral whey neutralized sporozoites more rapidly and completely than immune serum, monoclonal antibody (MAb) 18.44, or a combination of MAb 18.44 and MAb 17.41. Mice were partially protected against oral challenge with C. parvum oocysts when treated with immune colostral whey, MAb 17.41, or a combination of MAb 17.41 and MAb 18.44.

Original languageEnglish (US)
Pages (from-to)257-259
Number of pages3
JournalInfection and Immunity
Volume58
Issue number1
StatePublished - 1990
Externally publishedYes

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Cryptosporidium parvum
Sporozoites
Colostrum
Immune Sera
Monoclonal Antibodies
Oocysts

ASJC Scopus subject areas

  • Immunology

Cite this

Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum. / Perryman, L. E.; Riggs, Michael W; Mason, P. H.; Fayer, R.

In: Infection and Immunity, Vol. 58, No. 1, 1990, p. 257-259.

Research output: Contribution to journalArticle

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