Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum

L. E. Perryman, M. W. Riggs, P. H. Mason, R. Fayer

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

Monoclonal antibodies, immune bovine serum, and immune bovine colostral whey neutralized infectivity of Cryptosporidium parvum sporozoites for mice in a time-dependent manner. Immune colostral whey neutralized sporozoites more rapidly and completely than immune serum, monoclonal antibody (MAb) 18.44, or a combination of MAb 18.44 and MAb 17.41. Mice were partially protected against oral challenge with C. parvum oocysts when treated with immune colostral whey, MAb 17.41, or a combination of MAb 17.41 and MAb 18.44.

Original languageEnglish (US)
Pages (from-to)257-259
Number of pages3
JournalInfection and Immunity
Volume58
Issue number1
StatePublished - Jan 1 1990
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Kinetics of Cryptosporidium parvum sporozoite neutralization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum'. Together they form a unique fingerprint.

  • Cite this