L-trypiophan in neuroleptic-induced tardive dyskinesia

Reuven Sandyk, Colin R Bamford, Imran Khan, Hans Fisher

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Adminstration of the serotonin precursor L-tryptophan in a patient with neuroleptic-induced tardive dyskinesia, produced a dramatic reduction in the severity of the abnormal movements within 24 hours. This report supports our hypothesis that alterations in the function of serotoninergic neurotransmission are implicated in the pathophysiology of neuroleptic-induced tardive dyskinesia.

Original languageEnglish (US)
Pages (from-to)127-130
Number of pages4
JournalInternational Journal of Neuroscience
Volume42
Issue number1-2
DOIs
StatePublished - 1988

Fingerprint

Antipsychotic Agents
Dyskinesias
Synaptic Transmission
Tryptophan
Serotonin
Tardive Dyskinesia

Keywords

  • Dopamine
  • Iatrogenic disorder
  • L-tryptophan
  • Movement disorders
  • Serotonin
  • Tardive dyskinesia

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

L-trypiophan in neuroleptic-induced tardive dyskinesia. / Sandyk, Reuven; Bamford, Colin R; Khan, Imran; Fisher, Hans.

In: International Journal of Neuroscience, Vol. 42, No. 1-2, 1988, p. 127-130.

Research output: Contribution to journalArticle

Sandyk, Reuven ; Bamford, Colin R ; Khan, Imran ; Fisher, Hans. / L-trypiophan in neuroleptic-induced tardive dyskinesia. In: International Journal of Neuroscience. 1988 ; Vol. 42, No. 1-2. pp. 127-130.
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