L-trypiophan in neuroleptic-induced tardive dyskinesia

Reuven Sandyk, Colin R. Bamford, Imran Khan, Hans Fisher

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Adminstration of the serotonin precursor L-tryptophan in a patient with neuroleptic-induced tardive dyskinesia, produced a dramatic reduction in the severity of the abnormal movements within 24 hours. This report supports our hypothesis that alterations in the function of serotoninergic neurotransmission are implicated in the pathophysiology of neuroleptic-induced tardive dyskinesia.

Original languageEnglish (US)
Pages (from-to)127-130
Number of pages4
JournalInternational Journal of Neuroscience
Volume42
Issue number1-2
DOIs
StatePublished - Jan 1 1988

Keywords

  • Dopamine
  • Iatrogenic disorder
  • L-tryptophan
  • Movement disorders
  • Serotonin
  • Tardive dyskinesia

ASJC Scopus subject areas

  • Neuroscience(all)

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