Large monodomain bilayer arrays

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Described is a summary of methods to produce large monodomain bilayer arrays which contain a host of bioelectronic molecules between two supports such as glass, metal, or metal oxide surfaces. The methods involve the use of soap-based or silane polymer surfactants to render the contacting surfaces hydrophobic. The bilayer composition can be pure lipid; mixtures of lipid and protein, antibiotics, etc.; or purified proteins with bound lipid. Stacking of successive bilayers (or multiples of bilayers) having different copositions can be achieved by successive stages of annealing or shearing before adjustment of hydration. With these techniques, monodomain areas of approximately 1 cm2 and up to 500 μm thick can be achieved having a high density of bioelectronic molecules and varied composition.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual Conference on Engineering in Medicine and Biology
PublisherPubl by IEEE
Pages1746
Number of pages1
Editionpt 4
ISBN (Print)0879425598
StatePublished - 1990
Externally publishedYes
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Other

OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA
Period11/1/9011/4/90

Fingerprint

Lipids
Metals
Proteins
Silanes
Molecules
Soaps (detergents)
Antibiotics
Chemical analysis
Shearing
Surface-Active Agents
Hydration
Oxides
Polymers
Surface active agents
Annealing
Anti-Bacterial Agents
Glass

ASJC Scopus subject areas

  • Bioengineering

Cite this

Powers, L. S. (1990). Large monodomain bilayer arrays. In Proceedings of the Annual Conference on Engineering in Medicine and Biology (pt 4 ed., pp. 1746). Publ by IEEE.

Large monodomain bilayer arrays. / Powers, Linda S.

Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4. ed. Publ by IEEE, 1990. p. 1746.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Powers, LS 1990, Large monodomain bilayer arrays. in Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4 edn, Publ by IEEE, pp. 1746, Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Philadelphia, PA, USA, 11/1/90.
Powers LS. Large monodomain bilayer arrays. In Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4 ed. Publ by IEEE. 1990. p. 1746
Powers, Linda S. / Large monodomain bilayer arrays. Proceedings of the Annual Conference on Engineering in Medicine and Biology. pt 4. ed. Publ by IEEE, 1990. pp. 1746
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