Laser microsurgery in cell and developmental biology

Michael W. Berns, J. Aist, J. Edwards, K. Strahs, J. Girton, P. McNeill, J. B. Rattner, M. Kitzes, M. Hammer-Wilson, L. H. Liaw, A. Siemens, M. Koonce, S. Peterson, S. Brenner, J. Burt, R. Walter, P. J. Bryant, D. Van Dyk, J. Coulombe, T. CahillG. S. Berns

Research output: Contribution to journalReview article

185 Scopus citations

Abstract

New applications of laser microbeam irradiation to cell and developmental biology include a new instrument with a tunable wavelength (217- to 800-nanometer) laser microbeam and a wide range of energies and exposure durations (down to 25 × 10-12 second). Laser microbeams can be used for microirradiation of selected nucleolar genetic regions and for laser microdissection of mitotic and cytoplasmic organelles. They are also used to disrupt the developing neurosensory appendages of the cricket and the imaginai discs of Drosophila.

Original languageEnglish (US)
Pages (from-to)505-513
Number of pages9
JournalScience
Volume213
Issue number4507
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

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ASJC Scopus subject areas

  • General

Cite this

Berns, M. W., Aist, J., Edwards, J., Strahs, K., Girton, J., McNeill, P., Rattner, J. B., Kitzes, M., Hammer-Wilson, M., Liaw, L. H., Siemens, A., Koonce, M., Peterson, S., Brenner, S., Burt, J., Walter, R., Bryant, P. J., Van Dyk, D., Coulombe, J., ... Berns, G. S. (1981). Laser microsurgery in cell and developmental biology. Science, 213(4507), 505-513. https://doi.org/10.1126/science.7017933