"Later, lazier, and unluckier": A heuristic profile of high vulnerability is an independent predictor of uncontrolled blood pressure (the PREVIEW study)

Ivo L Abraham, Christopher Lee, Minkyoung Song, Stefaan Vancayzeele, Heidi Brié, Christine Hermans, Patricia van der Niepen, Karen MacDonald

Research output: Contribution to journalArticle

Abstract

Objective: Vulnerability profiling, an alternative to deterministic risk assessment, offers clinicians a more intuitive but empirically-grounded assessment of patient risk. This study aimed to determine whether a heuristic profile of high vulnerability is an independent predictor of uncontrolled hypertension. Methods: Secondary analysis of prospective observational study data on 2999 hypertensive patients treated with valsartan. Predictive validity of vulnerability profiling for first-line, secondline, and first-or-second-line antihypertensive treatment was inferred from 1) logistic regression models with adequate statistical fit, 2) statistically significant odds ratios for uncontrolled BP for the high-vulnerability cluster exceeding 1.00, and 3) correct classification rates for patients' BP control status. Results: All models of uncontrolled BP were significant (P<0.001); all odds ratios for the high-vulnerability cluster were greater than 1.00 and significant (P<0.001). Correct classification rates for the highly-vulnerability cluster on uncontrolled BP after first-line, second-line, or either treatment were 91.1%, 61.2%, and 93.5% for systolic BP; 74.5%, 65.8%, and 76.7% for diastolic BP; and 92.8%, 65.3%, and 94.6% for combined systolic and diastolic BP. Conclusion: The heuristic profile of "later, lazier, and unluckier" is an intuitive and valid tool to help identify patients at greater risk for poor BP control seen in general practice.

Original languageEnglish (US)
Pages (from-to)163-166
Number of pages4
JournalAmerican Journal of Clinical Hypnosis
Volume53
Issue number4
StatePublished - Apr 2011

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Blood Pressure
Valsartan
Logistic Models
Odds Ratio
General Practice
Antihypertensive Agents
Observational Studies
Prospective Studies
Hypertension
Heuristics
Therapeutics

Keywords

  • Heuristics
  • Hypertension
  • Profiling
  • Risk
  • Vulnerability

ASJC Scopus subject areas

  • Complementary and alternative medicine

Cite this

"Later, lazier, and unluckier" : A heuristic profile of high vulnerability is an independent predictor of uncontrolled blood pressure (the PREVIEW study). / Abraham, Ivo L; Lee, Christopher; Song, Minkyoung; Vancayzeele, Stefaan; Brié, Heidi; Hermans, Christine; van der Niepen, Patricia; MacDonald, Karen.

In: American Journal of Clinical Hypnosis, Vol. 53, No. 4, 04.2011, p. 163-166.

Research output: Contribution to journalArticle

Abraham, Ivo L ; Lee, Christopher ; Song, Minkyoung ; Vancayzeele, Stefaan ; Brié, Heidi ; Hermans, Christine ; van der Niepen, Patricia ; MacDonald, Karen. / "Later, lazier, and unluckier" : A heuristic profile of high vulnerability is an independent predictor of uncontrolled blood pressure (the PREVIEW study). In: American Journal of Clinical Hypnosis. 2011 ; Vol. 53, No. 4. pp. 163-166.
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