Ligand-controlled self-assembly of polynuclear lanthanide—oxo/hydroxo complexes: From synthetic serendipity to rational supramolecular design

Research output: Contribution to journalArticle

289 Scopus citations

Abstract

Lanthanide ions and complexes occupy a special position in developing synthetic nucleases capable of catalyzing the hydrolytic cleavage of RNA or DNA. Stimulated by a number of serendipitous lanthanide complexes that feature the common active-site structure of dinuclear metallo-phosphodiesterases, rational design and synthesis of polynuclear lanthanide—hydroxo species via ligand-controlled hydrolysis of the lanthanide ions were attempted. The efforts yielded a series of highly sophisticated yet structurally well-defined lanthanide—hydroxo complexes. These materials are potentially applicable to the study of biomimetic catalysis of phosphate diester cleavage. Research highlights are described in this Feature Article.

Original languageEnglish (US)
Pages (from-to)2521-2529
Number of pages9
JournalChemical Communications
Volume1
Issue number24
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Ligand-controlled self-assembly of polynuclear lanthanide—oxo/hydroxo complexes: From synthetic serendipity to rational supramolecular design'. Together they form a unique fingerprint.

  • Cite this