Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain

Henry I. Yamamura, Kelvin W. Gee, Roberta E. Brinton, Thomas P. Davis, Mac Hadley, James K. Wamsley

Research output: Contribution to journalArticle

55 Scopus citations

Abstract

Specific [3H]-arginine vasopressin ([3H]-AVP) binding sites were identified in the rat brain by light microscopic autoradiography. Discrete intrahypothalamic nuclei were densely labelled by [3H]-AVP. High specific binding was observed in the paraventricular and supraoptic nuclei. These binding sites may represent specific receptors for AVP, postulated to exist in the mammalian central nervous system.

Original languageEnglish (US)
Pages (from-to)1919-1924
Number of pages6
JournalLife Sciences
Volume32
Issue number16
DOIs
StatePublished - Apr 18 1983

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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