Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain

Henry I. Yamamura, Kelvin W. Gee, Roberta E. Brinton, Thomas P Davis, Mac Hadley, James K. Wamsley

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Specific [3H]-arginine vasopressin ([3H]-AVP) binding sites were identified in the rat brain by light microscopic autoradiography. Discrete intrahypothalamic nuclei were densely labelled by [3H]-AVP. High specific binding was observed in the paraventricular and supraoptic nuclei. These binding sites may represent specific receptors for AVP, postulated to exist in the mammalian central nervous system.

Original languageEnglish (US)
Pages (from-to)1919-1924
Number of pages6
JournalLife Sciences
Volume32
Issue number16
DOIs
StatePublished - Apr 18 1983

Fingerprint

Arginine Vasopressin
Rats
Brain
Visualization
Binding Sites
Light
Supraoptic Nucleus
Paraventricular Hypothalamic Nucleus
Neurology
Autoradiography
Central Nervous System

ASJC Scopus subject areas

  • Pharmacology

Cite this

Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain. / Yamamura, Henry I.; Gee, Kelvin W.; Brinton, Roberta E.; Davis, Thomas P; Hadley, Mac; Wamsley, James K.

In: Life Sciences, Vol. 32, No. 16, 18.04.1983, p. 1919-1924.

Research output: Contribution to journalArticle

Yamamura, Henry I. ; Gee, Kelvin W. ; Brinton, Roberta E. ; Davis, Thomas P ; Hadley, Mac ; Wamsley, James K. / Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain. In: Life Sciences. 1983 ; Vol. 32, No. 16. pp. 1919-1924.
@article{93e996a6770d4fb7a826031946128ce4,
title = "Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain",
abstract = "Specific [3H]-arginine vasopressin ([3H]-AVP) binding sites were identified in the rat brain by light microscopic autoradiography. Discrete intrahypothalamic nuclei were densely labelled by [3H]-AVP. High specific binding was observed in the paraventricular and supraoptic nuclei. These binding sites may represent specific receptors for AVP, postulated to exist in the mammalian central nervous system.",
author = "Yamamura, {Henry I.} and Gee, {Kelvin W.} and Brinton, {Roberta E.} and Davis, {Thomas P} and Mac Hadley and Wamsley, {James K.}",
year = "1983",
month = "4",
day = "18",
doi = "10.1016/0024-3205(83)90072-3",
language = "English (US)",
volume = "32",
pages = "1919--1924",
journal = "Life Sciences",
issn = "0024-3205",
publisher = "Elsevier Inc.",
number = "16",

}

TY - JOUR

T1 - Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain

AU - Yamamura, Henry I.

AU - Gee, Kelvin W.

AU - Brinton, Roberta E.

AU - Davis, Thomas P

AU - Hadley, Mac

AU - Wamsley, James K.

PY - 1983/4/18

Y1 - 1983/4/18

N2 - Specific [3H]-arginine vasopressin ([3H]-AVP) binding sites were identified in the rat brain by light microscopic autoradiography. Discrete intrahypothalamic nuclei were densely labelled by [3H]-AVP. High specific binding was observed in the paraventricular and supraoptic nuclei. These binding sites may represent specific receptors for AVP, postulated to exist in the mammalian central nervous system.

AB - Specific [3H]-arginine vasopressin ([3H]-AVP) binding sites were identified in the rat brain by light microscopic autoradiography. Discrete intrahypothalamic nuclei were densely labelled by [3H]-AVP. High specific binding was observed in the paraventricular and supraoptic nuclei. These binding sites may represent specific receptors for AVP, postulated to exist in the mammalian central nervous system.

UR - http://www.scopus.com/inward/record.url?scp=0020967888&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020967888&partnerID=8YFLogxK

U2 - 10.1016/0024-3205(83)90072-3

DO - 10.1016/0024-3205(83)90072-3

M3 - Article

C2 - 6300592

AN - SCOPUS:0020967888

VL - 32

SP - 1919

EP - 1924

JO - Life Sciences

JF - Life Sciences

SN - 0024-3205

IS - 16

ER -