Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement

Joseph Morelli, Hugh E. Mulcahy, Ira R. Willner, John T. Cunningham, Peter Draganov

Research output: Contribution to journalArticle

151 Scopus citations

Abstract

Background: Biliary stricture is one of the most common complications of liver transplantation. A number of treatment options are available, but a standard approach has not been established. Methods: A total of 25 patients with post-liver transplantation anastomotic strictures were treated endoscopically by stent placement. Long-term outcomes (bile duct patency, morbidity, and mortality) were reviewed retrospectively. Results: Placement of a stent was attempted in 25 patients with anastomotic stricture. Successful stent placement with stricture resolution at the time of stent removal was noted in 22 patients (technical success 88%). In those 22 patients, long-term success (mean follow-up after all stents removed, 54 months) was observed in 20 patients (90%) and partial success in two (10%). Long term, failure did not occur in any patient. There was no procedure- or disease-related mortally. Three mild episodes of cholangitis occurred during the period while the stents were in place, in relation to 79 endoscopic interventions for a procedure-related complication rate of 3.7%. Conclusions: The long-term outcome for patients with post-liver transplantation biliary anastomotic strictures treated with endoscopic stent placement is excellent, with no therapy- or disease-associated mortality and minimal morbidity.

Original languageEnglish (US)
Pages (from-to)374-379
Number of pages6
JournalGastrointestinal endoscopy
Volume58
Issue number3
DOIs
StatePublished - Sep 2003

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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