LP-BM5, a murine model of acquired immunodeficiency syndrome: Role of cocaine, morphine, alcohol and carotenoids in nutritional immunomodulation

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12 Scopus citations

Abstract

Potential immunomodulation by nutritional excesses and deficiencies can act as cofactors in human immunodeficient virus infection. The role of nutrition in the development and expression of acquired immunodeficiency syndrome (AIDS) is suggested and evaluated. LP-BM5 murine retroviral infection causes immune changes yielding an acquired immune deficiency syndrome with functional similarities to human AIDS. The value of the murine AIDS model to evaluate, rapidly, immune changes caused by potential cofactors, including nutritional changes, is illustrated.

Original languageEnglish (US)
Pages (from-to)744-748
Number of pages5
JournalJournal of Nutrition
Volume122
Issue number3 SUPPL.
DOIs
StatePublished - 1992

Keywords

  • acquired immunodeficiency syndrome
  • alcohol
  • cocaine
  • mice
  • retrovirus

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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