LP formulations for optimizing radiation treatment strategies

Benjamin Armbruster, Martin E. Lachaine, Russell J Hamilton, J. Cole Smith

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The goal of radiation therapy is to destroy the tumor with no side-effects. The recently developed technique of intensity modulated radiation therapy (IMRT) uses spatially nonuniform intensities. While this allows more flexibility and better treatments, it also increases the search space and hence requires optimization. We demonstrate the success of linear programming formulations in quickly finding acceptable plans. We believe this success stems from the natural way the constraints correspond to the physician's goals. In addition we present a novel objective that has a more natural spatial dependence than conventional penalty function formulations.

Original languageEnglish (US)
Title of host publicationIIE Annual Conference and Exhibition 2004
Pages1121-1124
Number of pages4
Publication statusPublished - 2004
EventIIE Annual Conference and Exhibition 2004 - Houston, TX, United States
Duration: May 15 2004May 19 2004

Other

OtherIIE Annual Conference and Exhibition 2004
CountryUnited States
CityHouston, TX
Period5/15/045/19/04

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Keywords

  • IMRT
  • Linear programming
  • Radiotherapy

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Armbruster, B., Lachaine, M. E., Hamilton, R. J., & Cole Smith, J. (2004). LP formulations for optimizing radiation treatment strategies. In IIE Annual Conference and Exhibition 2004 (pp. 1121-1124)