Lumpectomy and radiation treatment for invasive lobular carcinoma of the breast

James Warneke, Robert Berger, Cynthia Johnson, Dino Stea, Hugo Villar

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

BACKGROUND: Large studies have shown a similar outcome when comparing mastectomy with lumpectomy and external beam radiation therapy in the treatment of infiltrating ductal carcinoma. However, this has not been studied extensively for invasive lobular carcinoma. We studied the pattern of recurrence and overall survival of patients treated with lumpectomy and radiation for either invasive lobular carcinoma (ILC) or combined invasive lobular carcinoma/invasive ductal carcinoma (ILC/IDC) of the breast. DESIGN: A retrospective chart review was performed for 111 patients with ILC or ILC/IDC who were diagnosed and/or treated at the university hospital between 1984 and 1994. RESULTS: Of the 111 patients, 93 had stage I or II tumors. Thirty-four patients (37%) were treated with lumpectomy and adjuvant postoperative radiotherapy with one (3%) local recurrence and a mean overall survival of 83.6 months. Fifty-nine patients (63%) were treated by modified radical mastectomy with two local recurrences (3%) and a mean overall survival of 71.7 months. CONCLUSIONS: Patients with ILC or ILC/IDC can be effectively treated with lumpectomy and radiation for stage I and II tumors while maintaining a low risk of local recurrence and equivalent overall survival.

Original languageEnglish (US)
Pages (from-to)496-500
Number of pages5
JournalAmerican journal of surgery
Volume172
Issue number5
DOIs
StatePublished - Nov 1 1996

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Lumpectomy and radiation treatment for invasive lobular carcinoma of the breast'. Together they form a unique fingerprint.

  • Cite this