Lysogeny in nature: mechanisms, impact and ecology of temperate phages

Cristina Howard-Varona, Katherine R. Hargreaves, Stephen T. Abedon, Matthew Sullivan

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Viruses that infect bacteria (phages) can influence bacterial community dynamics, bacterial genome evolution and ecosystem biogeochemistry. These influences differ depending on whether phages establish lytic, chronic or lysogenic infections. Although the first two produce virion progeny, with lytic infections resulting in cell destruction, phages undergoing lysogenic infections replicate with cells without producing virions. The impacts of lysogeny are numerous and well-studied at the cellular level, but ecosystem-level consequences remain underexplored compared to those of lytic infections. Here, we review lysogeny from molecular mechanisms to ecological patterns to emerging approaches of investigation. Our goal is to highlight both its diversity and importance in complex communities. Altogether, using a combined viral ecology toolkit that is applied across broad model systems and environments will help us understand more of the diverse lifestyles and ecological impacts of lysogens in nature.The ISME Journal advance online publication, 14 March 2017; doi:10.1038/ismej.2017.16.

Original languageEnglish (US)
JournalISME Journal
DOIs
StateAccepted/In press - Mar 14 2017

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Lysogeny
lysogeny
Ecology
bacteriophages
Bacteriophages
ecology
Infection
virion
infection
Virion
Ecosystem
Bacterial Genomes
ecosystems
biogeochemistry
ecosystem
community dynamics
ecological impact
lifestyle
bacterial communities
Publications

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Lysogeny in nature : mechanisms, impact and ecology of temperate phages. / Howard-Varona, Cristina; Hargreaves, Katherine R.; Abedon, Stephen T.; Sullivan, Matthew.

In: ISME Journal, 14.03.2017.

Research output: Contribution to journalArticle

Howard-Varona, Cristina ; Hargreaves, Katherine R. ; Abedon, Stephen T. ; Sullivan, Matthew. / Lysogeny in nature : mechanisms, impact and ecology of temperate phages. In: ISME Journal. 2017.
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