Magnetic particle enhanced microcantilever biosensor for rapid and sensitive E. coli detection

Vasco Polyzoev, Eniko Enikov, Brian Heinze, Jeong Yeol Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

This paper presents a novel concept for integrating a magnetic microparticle sandwich assay onto a microcantilever beam, towards rapid and sensitive detection of E. Coli. The gold coated surface of the microcantilever beam and the surface of superparamagnetic microparticles are functionalized with anti-E. coli IgG so that they bind only in presence of and via the E. coli. An external magnetic field produced by an electromagnet is used to enhance the microcantilever deflection, and an optical lever method is used to sensitively detect it.

Original languageEnglish (US)
Title of host publicationISOT 2009 - International Symposium on Optomechatronic Technologies
Pages387-391
Number of pages5
DOIs
StatePublished - Dec 31 2009
EventISOT 2009 - International Symposium on Optomechatronic Technologies - Istanbul, Turkey
Duration: Sep 21 2009Sep 23 2009

Publication series

NameISOT 2009 - International Symposium on Optomechatronic Technologies

Other

OtherISOT 2009 - International Symposium on Optomechatronic Technologies
CountryTurkey
CityIstanbul
Period9/21/099/23/09

Keywords

  • E. coli detection
  • Magnetic microparticles
  • Microcantilever sensor
  • Optical lever

ASJC Scopus subject areas

  • Hardware and Architecture
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'Magnetic particle enhanced microcantilever biosensor for rapid and sensitive E. coli detection'. Together they form a unique fingerprint.

  • Cite this

    Polyzoev, V., Enikov, E., Heinze, B., & Yoon, J. Y. (2009). Magnetic particle enhanced microcantilever biosensor for rapid and sensitive E. coli detection. In ISOT 2009 - International Symposium on Optomechatronic Technologies (pp. 387-391). [5326138] (ISOT 2009 - International Symposium on Optomechatronic Technologies). https://doi.org/10.1109/ISOT.2009.5326138