Management of early endometrial carcinoma

L. J Sant Cassia, Burkhard Weppelmann, Hugh Shingleton, S. J. Soong, Kenneth D Hatch, Merle M. Salter

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Management of early endometrial carcinoma is controversial in regard to timing and indication of adjunctive radiation therapy. Two hundred eighty patients with stage I carcinoma of the endometrium are analyzed: 135 patients were treated with surgery only and 61 patients underwent preoperative and 83 patients postoperative radiation therapy. The overall survival was 94%. Recurrence rates in all three treatment arms were equal. Tumor grade was found to change from the diagnostic D&C specimen to the definite surgical specimen in 31% of all cases and in 50% of all grade 3 lesions. As only 39% of all patients required post-operative radiation therapy with equal survival, a primary surgical approach spares the majority of patient unnecessary treatment and preserves prognostically important histology.

Original languageEnglish (US)
Pages (from-to)362-366
Number of pages5
JournalGynecologic Oncology
Volume35
Issue number3
DOIs
StatePublished - 1989
Externally publishedYes

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Endometrial Neoplasms
Radiotherapy
Survival
Histology
Recurrence
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Cassia, L. J. S., Weppelmann, B., Shingleton, H., Soong, S. J., Hatch, K. D., & Salter, M. M. (1989). Management of early endometrial carcinoma. Gynecologic Oncology, 35(3), 362-366. https://doi.org/10.1016/0090-8258(89)90080-2

Management of early endometrial carcinoma. / Cassia, L. J Sant; Weppelmann, Burkhard; Shingleton, Hugh; Soong, S. J.; Hatch, Kenneth D; Salter, Merle M.

In: Gynecologic Oncology, Vol. 35, No. 3, 1989, p. 362-366.

Research output: Contribution to journalArticle

Cassia, LJS, Weppelmann, B, Shingleton, H, Soong, SJ, Hatch, KD & Salter, MM 1989, 'Management of early endometrial carcinoma', Gynecologic Oncology, vol. 35, no. 3, pp. 362-366. https://doi.org/10.1016/0090-8258(89)90080-2
Cassia LJS, Weppelmann B, Shingleton H, Soong SJ, Hatch KD, Salter MM. Management of early endometrial carcinoma. Gynecologic Oncology. 1989;35(3):362-366. https://doi.org/10.1016/0090-8258(89)90080-2
Cassia, L. J Sant ; Weppelmann, Burkhard ; Shingleton, Hugh ; Soong, S. J. ; Hatch, Kenneth D ; Salter, Merle M. / Management of early endometrial carcinoma. In: Gynecologic Oncology. 1989 ; Vol. 35, No. 3. pp. 362-366.
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