Manipulation of clinical materials using AC electrokinetics

Mandy L Y Sin, Pak Kin Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

AC electrokinetics is a promising approach for sample preparation and reaction enhancement in lab-on-a-chip devices. However, relative little has been done on the electrokinetic manipulation of physiological fluids and buffers with similar properties, such as conductivity. Herein, electrokinetic manipulation of fluids with a wide range of conductivities has been studied as a function of voltage and frequency. AC electrothermal flow is determined to dominate the fluid motion when the applied frequency of the AC potential is above 100 kHz. Interestingly, experimental data deviate from theoretical prediction for fluids with high conductivities (> 1 Sm -1). The deviation can be understood by voltage modulated electrochemical reactions and should be accounted for when manipulating clinical materials with high conductivities. The study will provide useful in sights in designing lab-on-a-chip devices for manipulating clinical samples in the future.

Original languageEnglish (US)
Title of host publicationProceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010
Pages71-74
Number of pages4
StatePublished - 2010
Event1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010 - Houston, TX, United States
Duration: Feb 7 2010Feb 10 2010

Other

Other1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010
CountryUnited States
CityHouston, TX
Period2/7/102/10/10

Fingerprint

Equipment and Supplies
Lab-on-a-chip
Fluids
Buffers
Electric potential

ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine(all)

Cite this

Sin, M. L. Y., & Wong, P. K. (2010). Manipulation of clinical materials using AC electrokinetics. In Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010 (pp. 71-74)

Manipulation of clinical materials using AC electrokinetics. / Sin, Mandy L Y; Wong, Pak Kin.

Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. 2010. p. 71-74.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sin, MLY & Wong, PK 2010, Manipulation of clinical materials using AC electrokinetics. in Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. pp. 71-74, 1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010, Houston, TX, United States, 2/7/10.
Sin MLY, Wong PK. Manipulation of clinical materials using AC electrokinetics. In Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. 2010. p. 71-74
Sin, Mandy L Y ; Wong, Pak Kin. / Manipulation of clinical materials using AC electrokinetics. Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. 2010. pp. 71-74
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