Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects

Heidi - Mansour, MinJi Sohn, Abeer Al-Ghananeem, Patrick P. DeLuca

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

Original languageEnglish (US)
Pages (from-to)3298-3322
Number of pages25
JournalInternational Journal of Molecular Sciences
Volume11
Issue number9
DOIs
StatePublished - Sep 2010
Externally publishedYes

Fingerprint

Nanotechnology
Dosage Forms
Materials science
Drug delivery
Nanoparticles
Drug products
delivery
Polymers
drugs
dosage
microparticles
materials science
nanotechnology
Pharmaceutical Preparations
routes
engineering
nanoparticles
polymers
Therapeutics
products

Keywords

  • Biodegradable
  • Biomaterials
  • Copolymers
  • Manufacture
  • Microparticle
  • Nanoparticle
  • Particle engineering design
  • Pharmaceutical dosage forms
  • Polymers

ASJC Scopus subject areas

  • Computer Science Applications
  • Molecular Biology
  • Catalysis
  • Inorganic Chemistry
  • Spectroscopy
  • Organic Chemistry
  • Physical and Theoretical Chemistry

Cite this

Materials for pharmaceutical dosage forms : Molecular pharmaceutics and controlled release drug delivery aspects. / Mansour, Heidi -; Sohn, MinJi; Al-Ghananeem, Abeer; DeLuca, Patrick P.

In: International Journal of Molecular Sciences, Vol. 11, No. 9, 09.2010, p. 3298-3322.

Research output: Contribution to journalArticle

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