Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects

Heidi M. Mansour, Min Ji Sohn, Abeer Al-Ghananeem, Patrick P. DeLuca

Research output: Contribution to journalReview article

122 Scopus citations

Abstract

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

Original languageEnglish (US)
Pages (from-to)3298-3322
Number of pages25
JournalInternational journal of molecular sciences
Volume11
Issue number9
DOIs
StatePublished - Sep 2010

Keywords

  • Biodegradable
  • Biomaterials
  • Copolymers
  • Manufacture
  • Microparticle
  • Nanoparticle
  • Particle engineering design
  • Pharmaceutical dosage forms
  • Polymers

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint Dive into the research topics of 'Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects'. Together they form a unique fingerprint.

  • Cite this