Maternal phenylketonuria

Christopher M Cunniff, Jaime L. Frias, Celia Kaye, John B. Moeschler, Susan R. Panny, Tracy L. Trotter, Felix De La Cruz, John Williams, James W. Hanson, Cynthia A. Moore, Michele Lloyd-Puryear, H. Eugene Hoyme, Rebecca S. Wappner, Lauri Hall

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Elevated maternal phenylalanine levels during pregnancy are teratogenic and may result in growth retardation, significant psychomotor handicaps, and birth defects in the offspring of unmonitored and untreated pregnancies. Women of childbearing age with all forms of phenylketonuria, including mild variants such as hyperphenylalaninemia, should receive counseling concerning their risks for adverse fetal effects optimally before conceiving. The best outcomes occur when strict control of maternal phenylalanine levels is achieved before conception and continued throughout the pregnancy.

Original languageEnglish (US)
Pages (from-to)427-428
Number of pages2
JournalPediatrics
Volume107
Issue number2
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Maternal Phenylketonuria
Phenylketonurias
Phenylalanine
Pregnancy
Mothers
Counseling
Growth

Keywords

  • PAH
  • Phe
  • Phenylalanine
  • Phenylalanine hydroxylase
  • Phenylketonuria
  • PKU

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Cunniff, C. M., Frias, J. L., Kaye, C., Moeschler, J. B., Panny, S. R., Trotter, T. L., ... Hall, L. (2001). Maternal phenylketonuria. Pediatrics, 107(2), 427-428. https://doi.org/10.1542/peds.107.2.427

Maternal phenylketonuria. / Cunniff, Christopher M; Frias, Jaime L.; Kaye, Celia; Moeschler, John B.; Panny, Susan R.; Trotter, Tracy L.; De La Cruz, Felix; Williams, John; Hanson, James W.; Moore, Cynthia A.; Lloyd-Puryear, Michele; Hoyme, H. Eugene; Wappner, Rebecca S.; Hall, Lauri.

In: Pediatrics, Vol. 107, No. 2, 2001, p. 427-428.

Research output: Contribution to journalArticle

Cunniff, CM, Frias, JL, Kaye, C, Moeschler, JB, Panny, SR, Trotter, TL, De La Cruz, F, Williams, J, Hanson, JW, Moore, CA, Lloyd-Puryear, M, Hoyme, HE, Wappner, RS & Hall, L 2001, 'Maternal phenylketonuria', Pediatrics, vol. 107, no. 2, pp. 427-428. https://doi.org/10.1542/peds.107.2.427
Cunniff CM, Frias JL, Kaye C, Moeschler JB, Panny SR, Trotter TL et al. Maternal phenylketonuria. Pediatrics. 2001;107(2):427-428. https://doi.org/10.1542/peds.107.2.427
Cunniff, Christopher M ; Frias, Jaime L. ; Kaye, Celia ; Moeschler, John B. ; Panny, Susan R. ; Trotter, Tracy L. ; De La Cruz, Felix ; Williams, John ; Hanson, James W. ; Moore, Cynthia A. ; Lloyd-Puryear, Michele ; Hoyme, H. Eugene ; Wappner, Rebecca S. ; Hall, Lauri. / Maternal phenylketonuria. In: Pediatrics. 2001 ; Vol. 107, No. 2. pp. 427-428.
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