Maternal phenylketonuria

Implications for growth and development

William K. Frankenburg, Burris R Duncan, R. Wendell Coffelt, Richard Koch, James G. Coldwell, Choon D. Son

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Eight non-PKU offspring of phenylketonuric mothers are described. All of the patients have mental subnormality and I.Q./D.Q. scores below those of their mothers. Phenylalanine loading tests failed to discriminate between the nonheterozygotes and the heterozygotes. Growth data from these cases and additional previously unpublished growth data on 13 non-PKU offspring of 3 phenylketonuric mothers demonstrated uniform intrauterine and postnatal growth retardation.

Original languageEnglish (US)
Pages (from-to)560-570
Number of pages11
JournalThe Journal of Pediatrics
Volume73
Issue number4
StatePublished - Oct 1968
Externally publishedYes

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Maternal Phenylketonuria
Growth and Development
Mothers
Fetal Growth Retardation
Mentally Ill Persons
Heterozygote
Growth
Phenylalanine

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Frankenburg, W. K., Duncan, B. R., Coffelt, R. W., Koch, R., Coldwell, J. G., & Son, C. D. (1968). Maternal phenylketonuria: Implications for growth and development. The Journal of Pediatrics, 73(4), 560-570.

Maternal phenylketonuria : Implications for growth and development. / Frankenburg, William K.; Duncan, Burris R; Coffelt, R. Wendell; Koch, Richard; Coldwell, James G.; Son, Choon D.

In: The Journal of Pediatrics, Vol. 73, No. 4, 10.1968, p. 560-570.

Research output: Contribution to journalArticle

Frankenburg, WK, Duncan, BR, Coffelt, RW, Koch, R, Coldwell, JG & Son, CD 1968, 'Maternal phenylketonuria: Implications for growth and development', The Journal of Pediatrics, vol. 73, no. 4, pp. 560-570.
Frankenburg WK, Duncan BR, Coffelt RW, Koch R, Coldwell JG, Son CD. Maternal phenylketonuria: Implications for growth and development. The Journal of Pediatrics. 1968 Oct;73(4):560-570.
Frankenburg, William K. ; Duncan, Burris R ; Coffelt, R. Wendell ; Koch, Richard ; Coldwell, James G. ; Son, Choon D. / Maternal phenylketonuria : Implications for growth and development. In: The Journal of Pediatrics. 1968 ; Vol. 73, No. 4. pp. 560-570.
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