TY - JOUR
T1 - Maximum-likelihood methods for processing signals from gamma-ray detectors
AU - Barrett, Harrison H.
AU - Hunter, William C.J.
AU - Miller, Brian William
AU - Moore, Stephen K.
AU - Chen, Yichun
AU - Furenlid, Lars R.
N1 - Funding Information:
Manuscript received July 14, 2008; revised November 26, 2008. Current version published June 10, 2009. This work was supported by the National Institutes of Health under Grant P41 EB002035.
PY - 2009/6
Y1 - 2009/6
N2 - In any gamma-ray detector, each event produces electrical signals on one or more circuit elements. From these signals, we may wish to determine the presence of an interaction; whether multiple interactions occurred; the spatial coordinates in two or three dimensions of at least the primary interaction; or the total energy deposited in that interaction. We may also want to compute listmode probabilities for tomographic reconstruction. Maximum-likelihood methods provide a rigorous and in some senses optimal approach to extracting this information, and the associated Fisher information matrix provides a way of quantifying and optimizing the information conveyed by the detector. This paper will review the principles of likelihood methods as applied to gamma-ray detectors and illustrate their power with recent results from the Center for Gamma-ray Imaging.
AB - In any gamma-ray detector, each event produces electrical signals on one or more circuit elements. From these signals, we may wish to determine the presence of an interaction; whether multiple interactions occurred; the spatial coordinates in two or three dimensions of at least the primary interaction; or the total energy deposited in that interaction. We may also want to compute listmode probabilities for tomographic reconstruction. Maximum-likelihood methods provide a rigorous and in some senses optimal approach to extracting this information, and the associated Fisher information matrix provides a way of quantifying and optimizing the information conveyed by the detector. This paper will review the principles of likelihood methods as applied to gamma-ray detectors and illustrate their power with recent results from the Center for Gamma-ray Imaging.
KW - Depth of interaction
KW - Gamma-ray detectors
KW - Maximum-likelihood estimation
KW - Scintillation cameras
KW - Semiconductor arrays
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U2 - 10.1109/TNS.2009.2015308
DO - 10.1109/TNS.2009.2015308
M3 - Article
AN - SCOPUS:67649322440
VL - 56
SP - 725
EP - 735
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
SN - 0018-9499
IS - 3
M1 - 5075989
ER -