Measurements of peripapillary nerve fiber layer contour in glaucoma

J. Caprioli, R. Ortiz-Colberg, Joseph M Miller, C. Tressler

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

We developed a method to quantify the surface contour of the peripapillary nerve fiber layer from simultaneous stereoscopic videographic images. Parameters that describe this contour are defined and compared to standard optic nerve structural parameters (cup/disk ratio, disk rim area, cup volume) in three age-matched groups of patients: 52 normal controls, 79 glaucoma suspects, and 101 glaucoma patients. Greater discriminatory information was obtained from the measurements from the superior and inferior quadrants than from the measurements from the temporal and nasal quadrants. This approach helps identify new structural markers that may more closely reflect the number of ganglion cell axons in the optic nerve. Such measurements made longitudinally in living eyes will provide valuable information about the relative rates of ganglion cell death in aging and in glaucoma.

Original languageEnglish (US)
Pages (from-to)404-413
Number of pages10
JournalAmerican Journal of Ophthalmology
Volume108
Issue number4
StatePublished - 1989
Externally publishedYes

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Optic Nerve
Nerve Fibers
Ganglia
Glaucoma
Living Wills
Ocular Hypertension
Nose
Axons
Cell Death
Research Design
Age Groups
Cell Count

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Caprioli, J., Ortiz-Colberg, R., Miller, J. M., & Tressler, C. (1989). Measurements of peripapillary nerve fiber layer contour in glaucoma. American Journal of Ophthalmology, 108(4), 404-413.

Measurements of peripapillary nerve fiber layer contour in glaucoma. / Caprioli, J.; Ortiz-Colberg, R.; Miller, Joseph M; Tressler, C.

In: American Journal of Ophthalmology, Vol. 108, No. 4, 1989, p. 404-413.

Research output: Contribution to journalArticle

Caprioli, J, Ortiz-Colberg, R, Miller, JM & Tressler, C 1989, 'Measurements of peripapillary nerve fiber layer contour in glaucoma', American Journal of Ophthalmology, vol. 108, no. 4, pp. 404-413.
Caprioli, J. ; Ortiz-Colberg, R. ; Miller, Joseph M ; Tressler, C. / Measurements of peripapillary nerve fiber layer contour in glaucoma. In: American Journal of Ophthalmology. 1989 ; Vol. 108, No. 4. pp. 404-413.
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